Rowland-Yeo K - Search Results

1

Advancing the utilization of real-world data and real-world evidence in clinical pharmacology and translational research-Proceedings from the ASCPT 2023 preconference workshop.

Liu J, Rowland-Yeo K, Winterstein A, Dagenais S, Liu Q, Barrett JS, Zhu R, Ghobadi C, Datta-Mannan A, Hsu J, Menon S, Ahmed M, Manchandani P, Ravenstijn P. Liu J, et al. Among authors: rowland yeo k. Clin Transl Sci. 2024 Apr;17(4):e13785. doi: 10.1111/cts.13785. Clin Transl Sci. 2024. PMID: 38572980 Free PMC article. Review.

2

Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.

Ghobadi C, Johnson TN, Aarabi M, Almond LM, Allabi AC, Rowland-Yeo K, Jamei M, Rostami-Hodjegan A. Ghobadi C, et al. Clin Pharmacokinet. 2011 Dec 1;50(12):809-22. doi: 10.2165/11594420-000000000-00000. Clin Pharmacokinet. 2011. PMID: 22087867

3

How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach.

Johnson TN, Jamei M, Rowland-Yeo K. Johnson TN, et al. Drug Metab Dispos. 2016 Jul;44(7):1090-8. doi: 10.1124/dmd.115.068643. Epub 2016 Feb 9. Drug Metab Dispos. 2016. PMID: 26862026

4

A best practice framework for applying physiologically-based pharmacokinetic modeling to pediatric drug development.

Johnson TN, Small BG, Berglund EG, Rowland Yeo K. Johnson TN, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):967-972. doi: 10.1002/psp4.12678. Epub 2021 Jul 20. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34288581 Free PMC article.

5

Dose Optimization Informed by PBPK Modeling: State-of-the Art and Future.

Rowland Yeo K, Gil Bergland E, Chen Y. Rowland Yeo K, et al. Clin Pharmacol Ther. 2024 Apr 30. doi: 10.1002/cpt.3289. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38686708 Review.

6

Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations.

Johnson TN, Small BG, Rowland Yeo K. Johnson TN, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11(3):373-383. doi: 10.1002/psp4.12764. Epub 2022 Feb 17. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35174656 Free PMC article.

7

Development and application of a PBPK modeling strategy to support antimalarial drug development.

Abla N, Howgate E, Rowland-Yeo K, Dickins M, Bergagnini-Kolev MC, Chen KF, McFeely S, Bonner JJ, Santos LGA, Gobeau N, Burt H, Barter Z, Jones HM, Wesche D, Charman SA, Möhrle JJ, Burrows JN, Almond LM. Abla N, et al. Among authors: rowland yeo k. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1335-1346. doi: 10.1002/psp4.13013. Epub 2023 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37587640 Free PMC article.

8

Physiologically Based Pharmacokinetic Modeling to Determine the Impact of CYP2B6 Genotype on Efavirenz Exposure in Children, Mothers and Breastfeeding Infants.

Pan X, Rowland Yeo K. Pan X, et al. Among authors: rowland yeo k. Clin Pharmacol Ther. 2023 Jul;114(1):182-191. doi: 10.1002/cpt.2912. Epub 2023 May 10. Clin Pharmacol Ther. 2023. PMID: 37078251

9

Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6.

Ke A, Barter Z, Rowland-Yeo K, Almond L. Ke A, et al. CPT Pharmacometrics Syst Pharmacol. 2016 Jul;5(7):367-76. doi: 10.1002/psp4.12088. Epub 2016 Jul 20. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27435752 Free PMC article.

10

Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling.

Rowland Yeo K, Zhang M, Pan X, Ban Ke A, Jones HM, Wesche D, Almond LM. Rowland Yeo K, et al. Clin Pharmacol Ther. 2020 Nov;108(5):976-984. doi: 10.1002/cpt.1955. Epub 2020 Jul 16. Clin Pharmacol Ther. 2020. PMID: 32531808 Free PMC article.

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