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Identification of RSK substrates using an analog-sensitive kinase approach.
Lizcano-Perret B, Vertommen D, Herinckx G, Calabrese V, Gatto L, Roux PP, Michiels T. Lizcano-Perret B, et al. Among authors: roux pp. J Biol Chem. 2024 Mar;300(3):105739. doi: 10.1016/j.jbc.2024.105739. Epub 2024 Feb 10. J Biol Chem. 2024. PMID: 38342435 Free PMC article.
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.
Goyette MA, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault MP, Johnson RM, Carmeliet P, Basik M, Gaboury L, Muller WJ, Park M, Roux PP, Gratton JP, Côté JF. Goyette MA, et al. Among authors: roux pp. Cell Rep. 2023 Dec 26;42(12):113604. doi: 10.1016/j.celrep.2023.113604. Epub 2023 Dec 14. Cell Rep. 2023. PMID: 38100352 Free article. No abstract available.
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard É, Thibault P, Bonneil É, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith MA, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm BT, Cellot S. Gress V, et al. Among authors: roux pp. Blood Adv. 2024 Jan 9;8(1):112-129. doi: 10.1182/bloodadvances.2022008899. Blood Adv. 2024. PMID: 37729615 Free PMC article.
Author Correction: In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.
Dervovic D, Malik AA, Chen ELY, Narimatsu M, Adler N, Afiuni-Zadeh S, Krenbek D, Martinez S, Tsai R, Boucher J, Berman JM, Teng K, Ayyaz A, Lü Y, Mbamalu G, Loganathan SK, Lee J, Zhang L, Guidos C, Wrana J, Valipour A, Roux PP, Reimand J, Jackson HW, Schramek D. Dervovic D, et al. Among authors: roux pp. Nat Commun. 2023 Sep 5;14(1):5404. doi: 10.1038/s41467-023-41255-0. Nat Commun. 2023. PMID: 37670013 Free PMC article. No abstract available.
HER2Δ16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer.
Attalla SS, Boucher J, Proud H, Taifour T, Zuo D, Sanguin-Gendreau V, Ling C, Johnson G, Li V, Luo RB, Kuasne H, Papavasiliou V, Walsh LA, Barok M, Joensuu H, Park M, Roux PP, Muller WJ. Attalla SS, et al. Among authors: roux pp. Cancer Immunol Res. 2023 Sep 1;11(9):1184-1202. doi: 10.1158/2326-6066.CIR-22-0140. Cancer Immunol Res. 2023. PMID: 37311021
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.
Dervovic D, Malik AA, Chen ELY, Narimatsu M, Adler N, Afiuni-Zadeh S, Krenbek D, Martinez S, Tsai R, Boucher J, Berman JM, Teng K, Ayyaz A, Lü Y, Mbamalu G, Loganathan SK, Lee J, Zhang L, Guidos C, Wrana J, Valipour A, Roux PP, Reimand J, Jackson HW, Schramek D. Dervovic D, et al. Among authors: roux pp. Nat Commun. 2023 May 31;14(1):3150. doi: 10.1038/s41467-023-38841-7. Nat Commun. 2023. PMID: 37258521 Free PMC article.
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.
Houles T, Lavoie G, Nourreddine S, Cheung W, Vaillancourt-Jean É, Guérin CM, Bouttier M, Grondin B, Lin S, Saba-El-Leil MK, Angers S, Meloche S, Roux PP. Houles T, et al. Among authors: roux pp. Nat Commun. 2022 Oct 29;13(1):6457. doi: 10.1038/s41467-022-34179-8. Nat Commun. 2022. PMID: 36309522 Free PMC article.
106 results