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Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. Among authors: routh al. PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627. eCollection 2022 Jun. PLoS Pathog. 2022. PMID: 35728038 Free PMC article.
Dengue NS2A Protein Orchestrates Virus Assembly.
Xie X, Zou J, Zhang X, Zhou Y, Routh AL, Kang C, Popov VL, Chen X, Wang QY, Dong H, Shi PY. Xie X, et al. Among authors: routh al. Cell Host Microbe. 2019 Nov 13;26(5):606-622.e8. doi: 10.1016/j.chom.2019.09.015. Epub 2019 Oct 17. Cell Host Microbe. 2019. PMID: 31631053 Free article.
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: routh al. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.268854. doi: 10.1101/2020.08.26.268854. bioRxiv. 2020. PMID: 32869021 Free PMC article. Updated. Preprint.
Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity.
Kozlova EV, Hegde S, Roundy CM, Golovko G, Saldaña MA, Hart CE, Anderson ER, Hornett EA, Khanipov K, Popov VL, Pimenova M, Zhou Y, Fovanov Y, Weaver SC, Routh AL, Heinz E, Hughes GL. Kozlova EV, et al. Among authors: routh al. ISME J. 2021 Jan;15(1):93-108. doi: 10.1038/s41396-020-00763-3. Epub 2020 Sep 7. ISME J. 2021. PMID: 32895494 Free PMC article.
The coronavirus proofreading exoribonuclease mediates extensive viral recombination.
Gribble J, Stevens LJ, Agostini ML, Anderson-Daniels J, Chappell JD, Lu X, Pruijssers AJ, Routh AL, Denison MR. Gribble J, et al. Among authors: routh al. PLoS Pathog. 2021 Jan 19;17(1):e1009226. doi: 10.1371/journal.ppat.1009226. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465137 Free PMC article.
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: routh al. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants.
Jaworski E, Langsjoen RM, Mitchell B, Judy B, Newman P, Plante JA, Plante KS, Miller AL, Zhou Y, Swetnam D, Sotcheff S, Morris V, Saada N, Machado R, McConnell A, Widen S, Thompson J, Dong J, Ren P, Pyles RB, Ksiazek T, Menachery VD, Weaver SC, Routh A. Jaworski E, et al. Among authors: routh a. bioRxiv [Preprint]. 2021 Sep 1:2021.03.10.434828. doi: 10.1101/2021.03.10.434828. bioRxiv. 2021. PMID: 33758846 Free PMC article. Updated. Preprint.
Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
Muruato A, Vu MN, Johnson BA, Davis-Gardner ME, Vanderheiden A, Lokugmage K, Schindewolf C, Crocquet-Valdes PA, Langsjoen RM, Plante JA, Plante KS, Weaver SC, Debbink K, Routh AL, Walker D, Suthar MS, Xie X, Shi PY, Xie X, Menachery VD. Muruato A, et al. Among authors: routh al. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442357. doi: 10.1101/2021.05.03.442357. bioRxiv. 2021. PMID: 33972939 Free PMC article. Updated. Preprint.
54 results