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Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma.
Khang M, Lee JH, Lee T, Suh HW, Lee S, Cavaliere A, Rushing A, Geraldo LH, Belitzky E, Rossano S, de Feyter HM, Shin K, Huttner A, Roussel MF, Thomas JL, Carson RE, Marquez-Nostra B, Bindra RS, Saltzman WM. Khang M, et al. Among authors: roussel mf. Sci Transl Med. 2023 Nov;15(720):eadi1617. doi: 10.1126/scitranslmed.adi1617. Epub 2023 Nov 1. Sci Transl Med. 2023. PMID: 37910601 Free PMC article.
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition.
Shendy NAM, Bikowitz M, Sigua LH, Zhang Y, Mercier A, Khashana Y, Nance S, Liu Q, Delahunty IM, Robinson S, Goel V, Rees MG, Ronan MA, Wang T, Kocak M, Roth JA, Wang Y, Freeman BB, Orr BA, Abraham BJ, Roussel MF, Schonbrunn E, Qi J, Durbin AD. Shendy NAM, et al. Among authors: roussel mf. Nat Commun. 2024 Apr 25;15(1):3483. doi: 10.1038/s41467-024-47102-0. Nat Commun. 2024. PMID: 38664416 Free PMC article.
Modeling pediatric medulloblastoma.
Roussel MF, Stripay JL. Roussel MF, et al. Brain Pathol. 2020 May;30(3):703-712. doi: 10.1111/bpa.12803. Epub 2019 Dec 17. Brain Pathol. 2020. PMID: 31788908 Free PMC article. Review.
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.
Endersby R, Whitehouse J, Pribnow A, Kuchibhotla M, Hii H, Carline B, Gande S, Stripay J, Ancliffe M, Howlett M, Schoep T, George C, Andradas C, Dyer P, Schluck M, Patterson B, Tacheva-Gigorova SK, Cooper MN, Robinson G, Stewart C, Pfister SM, Kool M, Milde T, Gajjar A, Johns T, Wechsler-Reya RJ, Roussel MF, Gottardo NG. Endersby R, et al. Among authors: roussel mf. Sci Transl Med. 2021 Jan 20;13(577):eaba7401. doi: 10.1126/scitranslmed.aba7401. Sci Transl Med. 2021. PMID: 33472956 Free PMC article.
Role of MYC in Medulloblastoma.
Roussel MF, Robinson GW. Roussel MF, et al. Cold Spring Harb Perspect Med. 2013 Nov 1;3(11):a014308. doi: 10.1101/cshperspect.a014308. Cold Spring Harb Perspect Med. 2013. PMID: 24186490 Free PMC article. Review.
Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.
Morfouace M, Shelat A, Jacus M, Freeman BB 3rd, Turner D, Robinson S, Zindy F, Wang YD, Finkelstein D, Ayrault O, Bihannic L, Puget S, Li XN, Olson JM, Robinson GW, Guy RK, Stewart CF, Gajjar A, Roussel MF. Morfouace M, et al. Among authors: roussel mf. Cancer Cell. 2014 Apr 14;25(4):516-29. doi: 10.1016/j.ccr.2014.02.009. Epub 2014 Mar 27. Cancer Cell. 2014. PMID: 24684846 Free PMC article.
Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma.
Pribnow A, Jonchere B, Liu J, Smith KS, Campagne O, Xu K, Robinson S, Patel Y, Onar-Thomas A, Wu G, Stewart CF, Northcott PA, Yu J, Robinson GW, Roussel MF. Pribnow A, et al. Among authors: roussel mf. Mol Cancer Ther. 2022 Aug 2;21(8):1306-1317. doi: 10.1158/1535-7163.MCT-21-0598. Mol Cancer Ther. 2022. PMID: 35709750 Free PMC article.
226 results