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MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat.
Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, Mosca R, Campos Y, Tillman H, Roussel MF, Andrew Weesner J, Ellen Fremuth L, Qiu X, Han MJ, Grosveld GC, d'Azzo A. Annunziata I, et al. Among authors: roussel mf. Nat Commun. 2019 Aug 9;10(1):3623. doi: 10.1038/s41467-019-11568-0. Nat Commun. 2019. PMID: 31399583 Free PMC article.
INK4d-deficient mice are fertile despite testicular atrophy.
Zindy F, van Deursen J, Grosveld G, Sherr CJ, Roussel MF. Zindy F, et al. Among authors: roussel mf. Mol Cell Biol. 2000 Jan;20(1):372-8. doi: 10.1128/MCB.20.1.372-378.2000. Mol Cell Biol. 2000. PMID: 10594039 Free PMC article.
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Gibson P, et al. Among authors: roussel mf. Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8. Nature. 2010. PMID: 21150899 Free PMC article.
A mouse model of the most aggressive subgroup of human medulloblastoma.
Kawauchi D, Robinson G, Uziel T, Gibson P, Rehg J, Gao C, Finkelstein D, Qu C, Pounds S, Ellison DW, Gilbertson RJ, Roussel MF. Kawauchi D, et al. Among authors: roussel mf. Cancer Cell. 2012 Feb 14;21(2):168-80. doi: 10.1016/j.ccr.2011.12.023. Cancer Cell. 2012. PMID: 22340591 Free PMC article.
Novel mutations target distinct subgroups of medulloblastoma.
Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, Thiruvenkatam R, Wang J, Wu G, Rusch M, Hong X, Becksfort J, Gupta P, Ma J, Easton J, Vadodaria B, Onar-Thomas A, Lin T, Li S, Pounds S, Paugh S, Zhao D, Kawauchi D, Roussel MF, Finkelstein D, Ellison DW, Lau CC, Bouffet E, Hassall T, Gururangan S, Cohn R, Fulton RS, Fulton LL, Dooling DJ, Ochoa K, Gajjar A, Mardis ER, Wilson RK, Downing JR, Zhang J, Gilbertson RJ. Robinson G, et al. Among authors: roussel mf. Nature. 2012 Aug 2;488(7409):43-8. doi: 10.1038/nature11213. Nature. 2012. PMID: 22722829 Free PMC article.
Miz1 is required to maintain autophagic flux.
Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, Renninger C, Krohne G, Asan E, Roussel MF, Eilers M. Wolf E, et al. Among authors: roussel mf. Nat Commun. 2013;4:2535. doi: 10.1038/ncomms3535. Nat Commun. 2013. PMID: 24088869 Free PMC article.
284 results