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Secretion of pro-angiogenic extracellular vesicles during hypoxia is dependent on the autophagy-related protein GABARAPL1.
Keulers TG, Libregts SF, Beaumont JEJ, Savelkouls KG, Bussink J, Duimel H, Dubois L, Zonneveld MI, López-Iglesias C, Bezstarosti K, Demmers JA, Vooijs M, Wauben M, Rouschop KMA. Keulers TG, et al. Among authors: rouschop kma. J Extracell Vesicles. 2021 Dec;10(14):e12166. doi: 10.1002/jev2.12166. J Extracell Vesicles. 2021. PMID: 34859607 Free PMC article.
Identification of Potential Prognostic and Predictive Immunological Biomarkers in Patients with Stage I and Stage III Non-Small Cell Lung Cancer (NSCLC): A Prospective Exploratory Study.
Vaes RDW, Reynders K, Sprooten J, Nevola KT, Rouschop KMA, Vooijs M, Garg AD, Lambrecht M, Hendriks LEL, Rucevic M, De Ruysscher D. Vaes RDW, et al. Among authors: rouschop kma. Cancers (Basel). 2021 Dec 13;13(24):6259. doi: 10.3390/cancers13246259. Cancers (Basel). 2021. PMID: 34944879 Free PMC article.
GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis development.
Beaumont JEJ, Ju J, Barbeau LMO, Demers I, Savelkouls KG, Derks K, Bouwman FG, Wauben MHM, Zonneveld MI, Keulers TGH, Rouschop KMA. Beaumont JEJ, et al. Among authors: rouschop kma. Radiother Oncol. 2024 Jan;190:109968. doi: 10.1016/j.radonc.2023.109968. Epub 2023 Oct 28. Radiother Oncol. 2024. PMID: 37898438 Free article.
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
67 results