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Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.
Cancer Res. 2020 Oct 1;80(19):4129-4144. doi: 10.1158/0008-5472.CAN-20-0471. Epub 2020 Aug 18.
Cancer Res. 2020.
PMID: 32816860
Copper: An Intracellular Achilles' Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics.
Michniewicz F, Saletta F, Rouaen JRC, Hewavisenti RV, Mercatelli D, Cirillo G, Giorgi FM, Trahair T, Ziegler D, Vittorio O.
Michniewicz F, et al. Among authors: rouaen jrc.
ChemMedChem. 2021 Aug 5;16(15):2315-2329. doi: 10.1002/cmdc.202100172. Epub 2021 Jun 1.
ChemMedChem. 2021.
PMID: 33890721
Review.
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Natural Polysaccharide Carriers in Brain Delivery: Challenge and Perspective.
Curcio M, Cirillo G, Rouaen JRC, Saletta F, Nicoletta FP, Vittorio O, Iemma F.
Curcio M, et al. Among authors: rouaen jrc.
Pharmaceutics. 2020 Dec 6;12(12):1183. doi: 10.3390/pharmaceutics12121183.
Pharmaceutics. 2020.
PMID: 33291284
Free PMC article.
Review.
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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Ehteda A, Simon S, Franshaw L, Giorgi FM, Liu J, Joshi S, Rouaen JRC, Pang CNI, Pandher R, Mayoh C, Tang Y, Khan A, Ung C, Tolhurst O, Kankean A, Hayden E, Lehmann R, Shen S, Gopalakrishnan A, Trebilcock P, Gurova K, Gudkov AV, Norris MD, Haber M, Vittorio O, Tsoli M, Ziegler DS.
Ehteda A, et al. Among authors: rouaen jrc.
Cell Rep. 2021 Apr 13;35(2):108994. doi: 10.1016/j.celrep.2021.108994.
Cell Rep. 2021.
PMID: 33852836
Free article.
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Systematic functional identification of cancer multi-drug resistance genes.
Lau MT, Ghazanfar S, Parkin A, Chou A, Rouaen JR, Littleboy JB, Nessem D, Khuong TM, Nevoltris D, Schofield P, Langley D, Christ D, Yang J, Pajic M, Neely GG.
Lau MT, et al.
Genome Biol. 2020 Feb 7;21(1):27. doi: 10.1186/s13059-020-1940-8.
Genome Biol. 2020.
PMID: 32028983
Free PMC article.
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Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer.
Poursani EM, Mercatelli D, Raninga P, Bell JL, Saletta F, Kohane FV, Neumann DP, Zheng Y, Rouaen JRC, Jue TR, Michniewicz FT, Schadel P, Kasiou E, Tsoli M, Cirillo G, Waters S, Shai-Hee T, Cazzoli R, Brettle M, Slapetova I, Kasherman M, Whan R, Souza-Fonseca-Guimaraes F, Vahdat L, Ziegler D, Lock JG, Giorgi FM, Khanna K, Vittorio O.
Poursani EM, et al. Among authors: rouaen jrc.
Cell Biosci. 2023 Jul 21;13(1):132. doi: 10.1186/s13578-023-01083-7.
Cell Biosci. 2023.
PMID: 37480151
Free PMC article.
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