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1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis.
Zhang L, Brodney MA, Candler J, Doran AC, Duplantier AJ, Efremov IV, Evrard E, Kraus K, Ganong AH, Haas JA, Hanks AN, Jenza K, Lazzaro JT, Maklad N, McCarthy SA, Qian W, Rogers BN, Rottas MD, Schmidt CJ, Siuciak JA, Tingley FD 3rd, Zhang AQ. Zhang L, et al. Among authors: rottas md. J Med Chem. 2011 Mar 24;54(6):1724-39. doi: 10.1021/jm101414h. Epub 2011 Mar 2. J Med Chem. 2011. PMID: 21366332
Demographic diversity of participants in Pfizer sponsored clinical trials in the United States.
Rottas M, Thadeio P, Simons R, Houck R, Gruben D, Keller D, Scholfield D, Soma K, Corrigan B, Schettino A, McCann PJ 3rd, Hellio MP, Natarajan K, Goodwin R, Sewards J, Honig P, MacKenzie R. Rottas M, et al. Contemp Clin Trials. 2021 Jul;106:106421. doi: 10.1016/j.cct.2021.106421. Epub 2021 Apr 30. Contemp Clin Trials. 2021. PMID: 33940253 Free article.