Rotili D - Search Results

1

Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling.

Illi B, Dello Russo C, Colussi C, Rosati J, Pallaoro M, Spallotta F, Rotili D, Valente S, Ragone G, Martelli F, Biglioli P, Steinkuhler C, Gallinari P, Mai A, Capogrossi MC, Gaetano C. Illi B, et al. Among authors: rotili d. Circ Res. 2008 Jan 4;102(1):51-8. doi: 10.1161/CIRCRESAHA.107.157305. Epub 2007 Nov 1. Circ Res. 2008. PMID: 17975112

2

Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity.

Fioravanti R, Proia E, Tyurenkov IN, Kurkin DV, Bakulin DA, Kovalev NS, Sheikin DS, Kirillov IA, Nawrozkij MB, Vernigora AA, Brunilina LL, Fiorentino F, Mladenović M, Rotili D, Ragno R. Fioravanti R, et al. Among authors: rotili d. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114902. doi: 10.1016/j.ejmech.2022.114902. Epub 2022 Nov 12. Eur J Med Chem. 2023. PMID: 36403514

3

Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A.

Mai A, Massa S, Pezzi R, Rotili D, Loidl P, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2003 Nov 6;46(23):4826-9. doi: 10.1021/jm034167p. J Med Chem. 2003. PMID: 14584932

4

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Among authors: rotili d. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

5

Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

Mai A, Massa S, Pezzi R, Simeoni S, Rotili D, Nebbioso A, Scognamiglio A, Altucci L, Loidl P, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2005 May 5;48(9):3344-53. doi: 10.1021/jm049002a. J Med Chem. 2005. PMID: 15857140

6

A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast.

Ornaghi P, Rotili D, Sbardella G, Mai A, Filetici P. Ornaghi P, et al. Among authors: rotili d. Biochem Pharmacol. 2005 Sep 15;70(6):911-7. doi: 10.1016/j.bcp.2005.06.013. Biochem Pharmacol. 2005. PMID: 16043126

7

Exploring the connection unit in the HDAC inhibitor pharmacophore model: novel uracil-based hydroxamates.

Mai A, Massa S, Rotili D, Pezzi R, Bottoni P, Scatena R, Meraner J, Brosch G. Mai A, et al. Among authors: rotili d. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4656-61. doi: 10.1016/j.bmcl.2005.07.081. Bioorg Med Chem Lett. 2005. PMID: 16165353

8

Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors.

Mai A, Massa S, Rotili D, Simeoni S, Ragno R, Botta G, Nebbioso A, Miceli M, Altucci L, Brosch G. Mai A, et al. Among authors: rotili d. J Med Chem. 2006 Oct 5;49(20):6046-56. doi: 10.1021/jm0605536. J Med Chem. 2006. PMID: 17004718

9

Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties.

Mai A, Rotili D, Tarantino D, Ornaghi P, Tosi F, Vicidomini C, Sbardella G, Nebbioso A, Miceli M, Altucci L, Filetici P. Mai A, et al. Among authors: rotili d. J Med Chem. 2006 Nov 16;49(23):6897-907. doi: 10.1021/jm060601m. J Med Chem. 2006. PMID: 17154519

10

Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans.

Mai A, Rotili D, Massa S, Brosch G, Simonetti G, Passariello C, Palamara AT. Mai A, et al. Among authors: rotili d. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1221-5. doi: 10.1016/j.bmcl.2006.12.028. Epub 2006 Dec 12. Bioorg Med Chem Lett. 2007. PMID: 17196388

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