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Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1.
Oetting A, Christiansen S, Gatzemeier F, Köcher S, Bußmann L, Böttcher A, Stölzel K, Hoffmann AS, Struve N, Kriegs M, Petersen C, Betz C, Rothkamm K, Zech HB, Rieckmann T. Oetting A, et al. Among authors: rothkamm k. Clin Transl Radiat Oncol. 2023 Apr 20;41:100630. doi: 10.1016/j.ctro.2023.100630. eCollection 2023 Jul. Clin Transl Radiat Oncol. 2023. PMID: 37180052 Free PMC article.
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease.
Elsesy ME, Oh-Hohenhorst SJ, Oing C, Eckhardt A, Burdak-Rothkamm S, Alawi M, Müller C, Schüller U, Maurer T, von Amsberg G, Petersen C, Rothkamm K, Mansour WY. Elsesy ME, et al. Among authors: rothkamm k. Mol Oncol. 2023 Jun;17(6):1129-1147. doi: 10.1002/1878-0261.13382. Epub 2023 Mar 16. Mol Oncol. 2023. PMID: 36694344 Free PMC article.
Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.
Classen S, Rahlf E, Jungwirth J, Albers N, Hebestreit LP, Zielinski A, Poole L, Groth M, Koch P, Liehr T, Kankel S, Cordes N, Petersen C, Rothkamm K, Pospiech H, Borgmann K. Classen S, et al. Among authors: rothkamm k. Int J Mol Sci. 2022 Nov 1;23(21):13363. doi: 10.3390/ijms232113363. Int J Mol Sci. 2022. PMID: 36362151 Free PMC article.
The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma.
Borgmann M, Oetting A, Meyer F, Möckelmann N, Droste C, von Bargen CM, Möller-Koop C, Witt M, Borgmann K, Rothkamm K, Betz C, Münscher A, Clauditz TS, Rieckmann T. Borgmann M, et al. Among authors: rothkamm k. J Cancer Res Clin Oncol. 2023 Jul;149(7):3383-3393. doi: 10.1007/s00432-022-04244-2. Epub 2022 Aug 8. J Cancer Res Clin Oncol. 2023. PMID: 35941227 Free PMC article.
A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells.
Köcher S, Zech HB, Krug L, Gatzemeier F, Christiansen S, Meyer F, Rietow R, Struve N, Mansour WY, Kriegs M, Petersen C, Betz C, Rothkamm K, Rieckmann T. Köcher S, et al. Among authors: rothkamm k. Front Oncol. 2022 May 31;12:765968. doi: 10.3389/fonc.2022.765968. eCollection 2022. Front Oncol. 2022. PMID: 35719921 Free PMC article.
136 results