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Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
Döhner K, Ramos-Nascimento A, Bialy D, Anderson F, Hickford-Martinez A, Rother F, Koithan T, Rudolph K, Buch A, Prank U, Binz A, Hügel S, Lebbink RJ, Hoeben RC, Hartmann E, Bader M, Bauerfeind R, Sodeik B. Döhner K, et al. Among authors: rother f. PLoS Pathog. 2018 Jan 5;14(1):e1006823. doi: 10.1371/journal.ppat.1006823. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29304174 Free PMC article.
Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa AS, Martin E, Martins IM, Schmidt J, Depping R, Weber JJ, Rother F, Hartmann E, Bader M, Riess O, Tricoire H, Schmidt T. Sowa AS, et al. Among authors: rother f. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2624-E2633. doi: 10.1073/pnas.1716071115. Epub 2018 Feb 23. Proc Natl Acad Sci U S A. 2018. PMID: 29476013 Free PMC article.
Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1.
Panayotis N, Sheinin A, Dagan SY, Tsoory MM, Rother F, Vadhvani M, Meshcheriakova A, Koley S, Marvaldi L, Song DA, Reuveny E, Eickholt BJ, Hartmann E, Bader M, Michaelevski I, Fainzilber M. Panayotis N, et al. Among authors: rother f. Cell Rep. 2018 Dec 11;25(11):3169-3179.e7. doi: 10.1016/j.celrep.2018.11.066. Cell Rep. 2018. PMID: 30540948 Free PMC article.
Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy.
Barros CC, Schadock I, Sihn G, Rother F, Xu P, Popova E, Lapidus I, Plehm R, Heuser A, Todiras M, Bachmann S, Alenina N, Araujo RC, Pesquero JB, Bader M. Barros CC, et al. Among authors: rother f. Front Med (Lausanne). 2018 Dec 3;5:338. doi: 10.3389/fmed.2018.00338. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30560131 Free PMC article.
Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection.
Thiele S, Stanelle-Bertram S, Beck S, Kouassi NM, Zickler M, Müller M, Tuku B, Resa-Infante P, van Riel D, Alawi M, Günther T, Rother F, Hügel S, Reimering S, McHardy A, Grundhoff A, Brune W, Osterhaus A, Bader M, Hartmann E, Gabriel G. Thiele S, et al. Among authors: rother f. Cell Rep. 2020 Apr 21;31(3):107549. doi: 10.1016/j.celrep.2020.107549. Cell Rep. 2020. PMID: 32320654 Free PMC article.
Importin α3 regulates chronic pain pathways in peripheral sensory neurons.
Marvaldi L, Panayotis N, Alber S, Dagan SY, Okladnikov N, Koppel I, Di Pizio A, Song DA, Tzur Y, Terenzio M, Rishal I, Gordon D, Rother F, Hartmann E, Bader M, Fainzilber M. Marvaldi L, et al. Among authors: rother f. Science. 2020 Aug 14;369(6505):842-846. doi: 10.1126/science.aaz5875. Science. 2020. PMID: 32792398
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