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Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function.
Kroschwald S, Chiu CY, Heydeck D, Rohwer N, Gehring T, Seifert U, Lux A, Rothe M, Weylandt KH, Kuhn H. Kroschwald S, et al. Among authors: rothe m. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug;1863(8):866-880. doi: 10.1016/j.bbalip.2018.04.019. Epub 2018 Apr 24. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29702245
Human lipoxygenase isoforms form complex patterns of double and triple oxygenated compounds from eicosapentaenoic acid.
Kutzner L, Goloshchapova K, Rund KM, Jübermann M, Blum M, Rothe M, Kirsch SF, Schunck WH, Kühn H, Schebb NH. Kutzner L, et al. Among authors: rothe m. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Dec;1865(12):158806. doi: 10.1016/j.bbalip.2020.158806. Epub 2020 Aug 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32841762
Oxygenation of endocannabinoids by mammalian lipoxygenase isoforms.
Ivanov I, Kakularam KR, Shmendel EV, Rothe M, Aparoy P, Heydeck D, Kuhn H. Ivanov I, et al. Among authors: rothe m. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jun;1866(6):158918. doi: 10.1016/j.bbalip.2021.158918. Epub 2021 Mar 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33662546
Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5-/- Mice.
Marbach-Breitrück E, Rohwer N, Infante-Duarte C, Romero-Suarez S, Labuz D, Machelska H, Kutzner L, Schebb NH, Rothe M, Reddanna P, Weylandt KH, Wieler LH, Heydeck D, Kuhn H. Marbach-Breitrück E, et al. Among authors: rothe m. Metabolites. 2021 Oct 12;11(10):698. doi: 10.3390/metabo11100698. Metabolites. 2021. PMID: 34677413 Free PMC article.
428 results