Roth JR - Search Results

1

Ohno's dilemma: evolution of new genes under continuous selection.

Bergthorsson U, Andersson DI, Roth JR. Bergthorsson U, et al. Among authors: roth jr. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17004-9. doi: 10.1073/pnas.0707158104. Epub 2007 Oct 17. Proc Natl Acad Sci U S A. 2007. PMID: 17942681 Free PMC article.

2

Amplification-mutagenesis: evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification.

Hendrickson H, Slechta ES, Bergthorsson U, Andersson DI, Roth JR. Hendrickson H, et al. Among authors: roth jr. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2164-9. doi: 10.1073/pnas.032680899. Epub 2002 Feb 5. Proc Natl Acad Sci U S A. 2002. PMID: 11830643 Free PMC article.

3

Multiple pathways of selected gene amplification during adaptive mutation.

Kugelberg E, Kofoid E, Reams AB, Andersson DI, Roth JR. Kugelberg E, et al. Among authors: roth jr. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17319-24. doi: 10.1073/pnas.0608309103. Epub 2006 Nov 2. Proc Natl Acad Sci U S A. 2006. PMID: 17082307 Free PMC article.

4

The effect of genomic position on reversion of a lac frameshift mutation (lacIZ33) during non-lethal selection (adaptive mutation).

Slechta ES, Harold J, Andersson DI, Roth JR. Slechta ES, et al. Among authors: roth jr. Mol Microbiol. 2002 May;44(4):1017-32. doi: 10.1046/j.1365-2958.2002.02934.x. Mol Microbiol. 2002. PMID: 12010495 Free article.

5

Adaptive mutation: general mutagenesis is not a programmed response to stress but results from rare coamplification of dinB with lac.

Slechta ES, Bunny KL, Kugelberg E, Kofoid E, Andersson DI, Roth JR. Slechta ES, et al. Among authors: roth jr. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12847-52. doi: 10.1073/pnas.1735464100. Epub 2003 Oct 14. Proc Natl Acad Sci U S A. 2003. PMID: 14559967 Free PMC article.

6

Amplification-mutagenesis--how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation.

Roth JR, Andersson DI. Roth JR, et al. Res Microbiol. 2004 Jun;155(5):342-51. doi: 10.1016/j.resmic.2004.01.016. Res Microbiol. 2004. PMID: 15207866 Free article. Review.

7

Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium.

Sun S, Berg OG, Roth JR, Andersson DI. Sun S, et al. Among authors: roth jr. Genetics. 2009 Aug;182(4):1183-95. doi: 10.1534/genetics.109.103028. Epub 2009 May 27. Genetics. 2009. PMID: 19474201 Free PMC article.

8

Real-time evolution of new genes by innovation, amplification, and divergence.

Näsvall J, Sun L, Roth JR, Andersson DI. Näsvall J, et al. Among authors: roth jr. Science. 2012 Oct 19;338(6105):384-7. doi: 10.1126/science.1226521. Science. 2012. PMID: 23087246 Free PMC article.

9

Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon.

Andersson DI, Slechta ES, Roth JR. Andersson DI, et al. Among authors: roth jr. Science. 1998 Nov 6;282(5391):1133-5. doi: 10.1126/science.282.5391.1133. Science. 1998. PMID: 9804552

10

Evidence that selected amplification of a bacterial lac frameshift allele stimulates Lac(+) reversion (adaptive mutation) with or without general hypermutability.

Slechta ES, Liu J, Andersson DI, Roth JR. Slechta ES, et al. Among authors: roth jr. Genetics. 2002 Jul;161(3):945-56. doi: 10.1093/genetics/161.3.945. Genetics. 2002. PMID: 12136002 Free PMC article.

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