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E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Pruenster M, Immler R, Roth J, Kuchler T, Bromberger T, Napoli M, Nussbaumer K, Rohwedder I, Wackerbarth LM, Piantoni C, Hennis K, Fink D, Kallabis S, Schroll T, Masgrau-Alsina S, Budke A, Liu W, Vestweber D, Wahl-Schott C, Roth J, Meissner F, Moser M, Vogl T, Hornung V, Broz P, Sperandio M. Pruenster M, et al. Among authors: roth j. Nat Immunol. 2023 Dec;24(12):2021-2031. doi: 10.1038/s41590-023-01656-1. Epub 2023 Oct 30. Nat Immunol. 2023. PMID: 37903858 Free PMC article.
Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. Jorch SK, et al. Among authors: roth j. J Allergy Clin Immunol. 2023 Jul;152(1):230-243. doi: 10.1016/j.jaci.2023.01.037. Epub 2023 Feb 22. J Allergy Clin Immunol. 2023. PMID: 36822481 Free article.
S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo.
Real F, Zhu A, Huang B, Belmellat A, Sennepin A, Vogl T, Ransy C, Revol M, Arrigucci R, Lombès A, Roth J, Gennaro ML, Bouillaud F, Cristofari S, Bomsel M. Real F, et al. Among authors: roth j. Nat Commun. 2022 Oct 11;13(1):5956. doi: 10.1038/s41467-022-33401-x. Nat Commun. 2022. PMID: 36220814 Free PMC article.
Systemic Activation of Neutrophils by Immune Complexes Is Critical to IgA Vasculitis.
Mayer-Hain S, Gebhardt K, Neufeld M, Ehrchen JM, Molyneux K, Barratt J, Nattkemper E, Gerloff D, Roth J, Vogl T, Pappelbaum KI, Sunderkötter C. Mayer-Hain S, et al. Among authors: roth j. J Immunol. 2022 Sep 15;209(6):1048-1058. doi: 10.4049/jimmunol.2100924. Epub 2022 Aug 19. J Immunol. 2022. PMID: 35985788
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis.
Ursino G, Ramadori G, Höfler A, Odouard S, Teixeira PDS, Visentin F, Veyrat-Durebex C, Lucibello G, Firnkes R, Ricci S, Vianna CR, Jia L, Dirlewanger M, Klee P, Elmquist JK, Roth J, Vogl T, Schwitzgebel VM, Jornayvaz FR, Boland A, Coppari R. Ursino G, et al. Among authors: roth j. Nat Commun. 2022 Jul 15;13(1):4107. doi: 10.1038/s41467-022-31803-5. Nat Commun. 2022. PMID: 35840613 Free PMC article.
Biallelic TLR4 deficiency in humans.
Capitani M, Al-Shaibi AA, Pandey S, Gartner L, Taylor H, Hubrack SZ, Agrebi N, Al-Mohannadi MJ, Al Kaabi S, Vogl T, Roth J, Kotlarz D, Klein C, Charles AK, Vijayakumar V, Karim MY, George B, Travis SP, Elawad M, Lo B, Uhlig HH. Capitani M, et al. Among authors: roth j. J Allergy Clin Immunol. 2023 Mar;151(3):783-790.e5. doi: 10.1016/j.jaci.2022.08.030. Epub 2022 Nov 30. J Allergy Clin Immunol. 2023. PMID: 36462956 Free article.
4,818 results