Roth A - Search Results

1

Translational precision medicine: an industry perspective.

Hartl D, de Luca V, Kostikova A, Laramie J, Kennedy S, Ferrero E, Siegel R, Fink M, Ahmed S, Millholland J, Schuhmacher A, Hinder M, Piali L, Roth A. Hartl D, et al. Among authors: roth a. J Transl Med. 2021 Jun 5;19(1):245. doi: 10.1186/s12967-021-02910-6. J Transl Med. 2021. PMID: 34090480 Free PMC article. Review.

2

Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.

McAleer CW, Long CJ, Elbrecht D, Sasserath T, Bridges LR, Rumsey JW, Martin C, Schnepper M, Wang Y, Schuler F, Roth AB, Funk C, Shuler ML, Hickman JJ. McAleer CW, et al. Sci Transl Med. 2019 Jun 19;11(497):eaav1386. doi: 10.1126/scitranslmed.aav1386. Sci Transl Med. 2019. PMID: 31217335

3

Challenging the pipeline.

Loskill P, Hardwick RN, Roth A. Loskill P, et al. Among authors: roth a. Stem Cell Reports. 2021 Sep 14;16(9):2033-2037. doi: 10.1016/j.stemcr.2021.08.004. Stem Cell Reports. 2021. PMID: 34525380 Free PMC article.

4

Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine.

Ruiz C, Kustermann S, Pietilae E, Vlajnic T, Baschiera B, Arabi L, Lorber T, Oeggerli M, Savic S, Obermann E, Singer T, Rothschild SI, Zippelius A, Roth AB, Bubendorf L. Ruiz C, et al. Among authors: roth ab. PLoS One. 2016 Aug 22;11(8):e0160807. doi: 10.1371/journal.pone.0160807. eCollection 2016. PLoS One. 2016. PMID: 27548442 Free PMC article.

5

The application of 3D cell models to support drug safety assessment: opportunities & challenges.

Roth A, Singer T. Roth A, et al. Adv Drug Deliv Rev. 2014 Apr;69-70:179-89. doi: 10.1016/j.addr.2013.12.005. Epub 2013 Dec 27. Adv Drug Deliv Rev. 2014. PMID: 24378580 Review.

6

Establishment of a translational endothelial cell model using directed differentiation of induced pluripotent stem cells from Cynomolgus monkey.

Thoma EC, Heckel T, Keller D, Giroud N, Leonard B, Christensen K, Roth A, Bertinetti-Lapatki C, Graf M, Patsch C. Thoma EC, et al. Among authors: roth a. Sci Rep. 2016 Oct 25;6:35830. doi: 10.1038/srep35830. Sci Rep. 2016. PMID: 27779219 Free PMC article.

7

Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry.

Baudy AR, Otieno MA, Hewitt P, Gan J, Roth A, Keller D, Sura R, Van Vleet TR, Proctor WR. Baudy AR, et al. Among authors: roth a. Lab Chip. 2020 Jan 21;20(2):215-225. doi: 10.1039/c9lc00768g. Epub 2019 Dec 4. Lab Chip. 2020. PMID: 31799979 Review.

8

Human microphysiological systems for drug development.

Roth A; MPS-WS Berlin 2019. Roth A, et al. Science. 2021 Sep 17;373(6561):1304-1306. doi: 10.1126/science.abc3734. Epub 2021 Sep 16. Science. 2021. PMID: 34529479

9

New approach methodologies in human regulatory toxicology - Not if, but how and when!

Schmeisser S, Miccoli A, von Bergen M, Berggren E, Braeuning A, Busch W, Desaintes C, Gourmelon A, Grafström R, Harrill J, Hartung T, Herzler M, Kass GEN, Kleinstreuer N, Leist M, Luijten M, Marx-Stoelting P, Poetz O, van Ravenzwaay B, Roggeband R, Rogiers V, Roth A, Sanders P, Thomas RS, Marie Vinggaard A, Vinken M, van de Water B, Luch A, Tralau T. Schmeisser S, et al. Among authors: roth a. Environ Int. 2023 Aug;178:108082. doi: 10.1016/j.envint.2023.108082. Epub 2023 Jul 4. Environ Int. 2023. PMID: 37422975 Free article. Review.

10

Current limitations and future opportunities for prediction of DILI from in vitro.

Funk C, Roth A. Funk C, et al. Among authors: roth a. Arch Toxicol. 2017 Jan;91(1):131-142. doi: 10.1007/s00204-016-1874-9. Epub 2016 Oct 20. Arch Toxicol. 2017. PMID: 27766365 Review.

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