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In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development.
Zane P, Gieschen H, Kersten E, Mathias N, Ollier C, Johansson P, Van den Bergh A, Van Hemelryck S, Reichel A, Rotgeri A, Schäfer K, Müllertz A, Langguth P. Zane P, et al. Among authors: rotgeri a. Eur J Pharm Biopharm. 2019 Sep;142:222-231. doi: 10.1016/j.ejpb.2019.06.010. Epub 2019 Jun 21. Eur J Pharm Biopharm. 2019. PMID: 31233862 Review.
Subcellular distribution of epothilones in human tumor cells.
Lichtner RB, Rotgeri A, Bunte T, Buchmann B, Hoffmann J, Schwede W, Skuballa W, Klar U. Lichtner RB, et al. Among authors: rotgeri a. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11743-8. doi: 10.1073/pnas.171023398. Epub 2001 Sep 18. Proc Natl Acad Sci U S A. 2001. PMID: 11562452 Free PMC article.
Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis.
Koppitz M, Bräuer N, Ter Laak A, Irlbacher H, Rotgeri A, Coelho AM, Walter D, Steinmeyer A, Zollner TM, Peters M, Nagel J. Koppitz M, et al. Among authors: rotgeri a. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2700-2705. doi: 10.1016/j.bmcl.2019.07.007. Epub 2019 Jul 24. Bioorg Med Chem Lett. 2019. PMID: 31362919
A prostaglandin E2 receptor antagonist prevents pregnancies during a preclinical contraceptive trial with female macaques.
Peluffo MC, Stanley J, Braeuer N, Rotgeri A, Fritzemeier KH, Fuhrmann U, Buchmann B, Adevai T, Murphy MJ, Zelinski MB, Lindenthal B, Hennebold JD, Stouffer RL. Peluffo MC, et al. Among authors: rotgeri a. Hum Reprod. 2014 Jul;29(7):1400-12. doi: 10.1093/humrep/deu083. Epub 2014 Apr 29. Hum Reprod. 2014. PMID: 24781425 Free PMC article.
Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist.
Mesch S, Walter D, Laux-Biehlmann A, Basting D, Flanagan S, Miyatake Ondozabal H, Bäurle S, Pearson C, Jenkins J, Elves P, Hess S, Coelho AM, Rotgeri A, Bothe U, Nawaz S, Zollner TM, Steinmeyer A. Mesch S, et al. Among authors: rotgeri a. J Med Chem. 2023 Jan 26;66(2):1583-1600. doi: 10.1021/acs.jmedchem.2c01830. Epub 2023 Jan 9. J Med Chem. 2023. PMID: 36622903 Free PMC article.
13 results