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The metalloproteinase ADAM10 requires its activity to sustain surface expression.
Seifert A, Düsterhöft S, Wozniak J, Koo CZ, Tomlinson MG, Nuti E, Rossello A, Cuffaro D, Yildiz D, Ludwig A. Seifert A, et al. Among authors: rossello a. Cell Mol Life Sci. 2021 Jan;78(2):715-732. doi: 10.1007/s00018-020-03507-w. Epub 2020 May 5. Cell Mol Life Sci. 2021. PMID: 32372373 Free PMC article.
N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis.
Nuti E, Casalini F, Avramova SI, Santamaria S, Cercignani G, Marinelli L, La Pietra V, Novellino E, Orlandini E, Nencetti S, Tuccinardi T, Martinelli A, Lim NH, Visse R, Nagase H, Rossello A. Nuti E, et al. Among authors: rossello a. J Med Chem. 2009 Aug 13;52(15):4757-73. doi: 10.1021/jm900261f. J Med Chem. 2009. PMID: 19606871
Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models.
Nuti E, Casalini F, Avramova SI, Santamaria S, Fabbi M, Ferrini S, Marinelli L, La Pietra V, Limongelli V, Novellino E, Cercignani G, Orlandini E, Nencetti S, Rossello A. Nuti E, et al. Among authors: rossello a. J Med Chem. 2010 Mar 25;53(6):2622-35. doi: 10.1021/jm901868z. J Med Chem. 2010. PMID: 20180536
138 results