Ross LS - Search Results

1

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages.

Bunnik EM, Cook KB, Varoquaux N, Batugedara G, Prudhomme J, Cort A, Shi L, Andolina C, Ross LS, Brady D, Fidock DA, Nosten F, Tewari R, Sinnis P, Ay F, Vert JP, Noble WS, Le Roch KG. Bunnik EM, et al. Among authors: ross ls. Nat Commun. 2018 May 15;9(1):1910. doi: 10.1038/s41467-018-04295-5. Nat Commun. 2018. PMID: 29765020 Free PMC article.

2

A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.

Witkowski B, Duru V, Khim N, Ross LS, Saintpierre B, Beghain J, Chy S, Kim S, Ke S, Kloeung N, Eam R, Khean C, Ken M, Loch K, Bouillon A, Domergue A, Ma L, Bouchier C, Leang R, Huy R, Nuel G, Barale JC, Legrand E, Ringwald P, Fidock DA, Mercereau-Puijalon O, Ariey F, Ménard D. Witkowski B, et al. Among authors: ross ls. Lancet Infect Dis. 2017 Feb;17(2):174-183. doi: 10.1016/S1473-3099(16)30415-7. Epub 2016 Nov 3. Lancet Infect Dis. 2017. PMID: 27818097 Free PMC article.

3

Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine.

Ross LS, Dhingra SK, Mok S, Yeo T, Wicht KJ, Kümpornsin K, Takala-Harrison S, Witkowski B, Fairhurst RM, Ariey F, Menard D, Fidock DA. Ross LS, et al. Nat Commun. 2018 Aug 17;9(1):3314. doi: 10.1038/s41467-018-05652-0. Nat Commun. 2018. PMID: 30115924 Free PMC article.

4

Comparative 3D genome organization in apicomplexan parasites.

Bunnik EM, Venkat A, Shao J, McGovern KE, Batugedara G, Worth D, Prudhomme J, Lapp SA, Andolina C, Ross LS, Lawres L, Brady D, Sinnis P, Nosten F, Fidock DA, Wilson EH, Tewari R, Galinski MR, Ben Mamoun C, Ay F, Le Roch KG. Bunnik EM, et al. Among authors: ross ls. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3183-3192. doi: 10.1073/pnas.1810815116. Epub 2019 Feb 5. Proc Natl Acad Sci U S A. 2019. PMID: 30723152 Free PMC article.

5

Elucidating Mechanisms of Drug-Resistant Plasmodium falciparum.

Ross LS, Fidock DA. Ross LS, et al. Cell Host Microbe. 2019 Jul 10;26(1):35-47. doi: 10.1016/j.chom.2019.06.001. Cell Host Microbe. 2019. PMID: 31295423 Free PMC article. Review.

6

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival.

Mok S, Stokes BH, Gnädig NF, Ross LS, Yeo T, Amaratunga C, Allman E, Solyakov L, Bottrill AR, Tripathi J, Fairhurst RM, Llinás M, Bozdech Z, Tobin AB, Fidock DA. Mok S, et al. Among authors: ross ls. Nat Commun. 2021 Jan 22;12(1):530. doi: 10.1038/s41467-020-20805-w. Nat Commun. 2021. PMID: 33483501 Free PMC article.

7

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites.

Dorjsuren D, Eastman RT, Wicht KJ, Jansen D, Talley DC, Sigmon BA, Zakharov AV, Roncal N, Girvin AT, Antonova-Koch Y, Will PM, Shah P, Sun H, Klumpp-Thomas C, Mok S, Yeo T, Meister S, Marugan JJ, Ross LS, Xu X, Maloney DJ, Jadhav A, Mott BT, Sciotti RJ, Winzeler EA, Waters NC, Campbell RF, Huang W, Simeonov A, Fidock DA. Dorjsuren D, et al. Among authors: ross ls. Sci Rep. 2021 Jan 22;11(1):2121. doi: 10.1038/s41598-021-81486-z. Sci Rep. 2021. PMID: 33483532 Free PMC article.

8

Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness.

Stokes BH, Dhingra SK, Rubiano K, Mok S, Straimer J, Gnädig NF, Deni I, Schindler KA, Bath JR, Ward KE, Striepen J, Yeo T, Ross LS, Legrand E, Ariey F, Cunningham CH, Souleymane IM, Gansané A, Nzoumbou-Boko R, Ndayikunda C, Kabanywanyi AM, Uwimana A, Smith SJ, Kolley O, Ndounga M, Warsame M, Leang R, Nosten F, Anderson TJ, Rosenthal PJ, Ménard D, Fidock DA. Stokes BH, et al. Among authors: ross ls. Elife. 2021 Jul 19;10:e66277. doi: 10.7554/eLife.66277. Elife. 2021. PMID: 34279219 Free PMC article.

9

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.

Mok S, Yeo T, Hong D, Shears MJ, Ross LS, Ward KE, Dhingra SK, Kanai M, Bridgford JL, Tripathi AK, Mlambo G, Burkhard AY, Ansbro MR, Fairhurst KJ, Gil-Iturbe E, Park H, Rozenberg FD, Kim J, Mancia F, Fairhurst RM, Quick M, Uhlemann AC, Sinnis P, Fidock DA. Mok S, et al. Among authors: ross ls. Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. Sci Adv. 2023. PMID: 37939186 Free PMC article.

10

Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.

Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH Jr, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R. Dong CK, et al. Chem Biol. 2011 Dec 23;18(12):1602-10. doi: 10.1016/j.chembiol.2011.09.016. Chem Biol. 2011. PMID: 22195562 Free PMC article.

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