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Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G. Moya IM, et al. Among authors: roskams t. Science. 2019 Nov 22;366(6468):1029-1034. doi: 10.1126/science.aaw9886. Science. 2019. PMID: 31754005
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas.
Govaere O, Komuta M, Berkers J, Spee B, Janssen C, de Luca F, Katoonizadeh A, Wouters J, van Kempen LC, Durnez A, Verslype C, De Kock J, Rogiers V, van Grunsven LA, Topal B, Pirenne J, Vankelecom H, Nevens F, van den Oord J, Pinzani M, Roskams T. Govaere O, et al. Among authors: roskams t. Gut. 2014 Apr;63(4):674-85. doi: 10.1136/gutjnl-2012-304351. Epub 2013 Aug 19. Gut. 2014. PMID: 23958557 Free PMC article.
Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.
Govaere O, Wouters J, Petz M, Vandewynckel YP, Van den Eynde K, Van den Broeck A, Verhulst S, Dollé L, Gremeaux L, Ceulemans A, Nevens F, van Grunsven LA, Topal B, Vankelecom H, Giannelli G, Van Vlierberghe H, Mikulits W, Komuta M, Roskams T. Govaere O, et al. Among authors: roskams t. J Hepatol. 2016 Mar;64(3):609-17. doi: 10.1016/j.jhep.2015.11.011. Epub 2015 Nov 17. J Hepatol. 2016. PMID: 26592953 Free article.
Hepatic Progenitor Cells: An Update.
Van Haele M, Roskams T. Van Haele M, et al. Among authors: roskams t. Gastroenterol Clin North Am. 2017 Jun;46(2):409-420. doi: 10.1016/j.gtc.2017.01.011. Gastroenterol Clin North Am. 2017. PMID: 28506372 Review.
394 results