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Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity.
Nat Med. 2022 Apr;28(4):766-779. doi: 10.1038/s41591-022-01680-y. Epub 2022 Feb 21.
Nat Med. 2022.
PMID: 35190725
Free PMC article.
Efficient long-term depletion of CD20+ B cells by rituximab does not affect gut-resident plasma cells.
Uzzan M, Ko HM, Rosenstein AK, Pourmand K, Colombel JF, Mehandru S.
Uzzan M, et al. Among authors: rosenstein ak.
Ann N Y Acad Sci. 2018 Mar;1415(1):5-10. doi: 10.1111/nyas.13577. Epub 2017 Dec 31.
Ann N Y Acad Sci. 2018.
PMID: 29291255
Free PMC article.
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The current state of the art for biological therapies and new small molecules in inflammatory bowel disease.
Paramsothy S, Rosenstein AK, Mehandru S, Colombel JF.
Paramsothy S, et al. Among authors: rosenstein ak.
Mucosal Immunol. 2018 Nov;11(6):1558-1570. doi: 10.1038/s41385-018-0050-3. Epub 2018 Jun 15.
Mucosal Immunol. 2018.
PMID: 29907872
Free PMC article.
Review.
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Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.
Uzzan M, Tokuyama M, Rosenstein AK, Tomescu C, SahBandar IN, Ko HM, Leyre L, Chokola A, Kaplan-Lewis E, Rodriguez G, Seki A, Corley MJ, Aberg J, La Porte A, Park EY, Ueno H, Oikonomou I, Doron I, Iliev ID, Chen BK, Lui J, Schacker TW, Furtado GC, Lira SA, Colombel JF, Horowitz A, Lim JK, Chomont N, Rahman AH, Montaner LJ, Ndhlovu LC, Mehandru S.
Uzzan M, et al. Among authors: rosenstein ak.
Sci Transl Med. 2018 Oct 3;10(461):eaau4711. doi: 10.1126/scitranslmed.aau4711.
Sci Transl Med. 2018.
PMID: 30282696
Free PMC article.
Clinical Trial.
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iTRAQ-based pharmacoproteomics reveals potential targets of berberine, a promising therapy for ulcerative colitis.
Li YH, Sun W, Zhou BJ, Rosenstein A, Zhao J, Wang J, Bian ZX.
Li YH, et al.
Eur J Pharmacol. 2019 May 5;850:167-179. doi: 10.1016/j.ejphar.2019.02.021. Epub 2019 Feb 14.
Eur J Pharmacol. 2019.
PMID: 30771347
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Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos A, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Nakadar MZ, Wong J, Erlich EC, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith J, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S.
Canales-Herrerias P, et al.
bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524731. doi: 10.1101/2023.01.19.524731.
bioRxiv. 2023.
PMID: 36711839
Free PMC article.
Updated.
Preprint.
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Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos AE, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Laurent T, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Taylor MD, Nakadar MZ, Wong J, Erlich EC, Mintz RL, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Ganjian D, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith JJ, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S.
Canales-Herrerias P, et al.
Sci Immunol. 2024 Apr 19;9(94):eadg7549. doi: 10.1126/sciimmunol.adg7549. Epub 2024 Apr 19.
Sci Immunol. 2024.
PMID: 38640252
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Alopecia areata universalis complicating daclizumab therapy for uveitis.
Rosenstein AK, Machler BC, Rosenstein ED.
Rosenstein AK, et al.
Cutis. 2014 May;93(5):E13-6.
Cutis. 2014.
PMID: 24897146
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