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The Extracellular Niche and Tumor Microenvironment Enhance KRAS Inhibitor Efficacy in Pancreatic Cancer.
Cancer Res. 2024 Apr 1;84(7):1115-1132. doi: 10.1158/0008-5472.CAN-23-2504.
Cancer Res. 2024.
PMID: 38294344
Free PMC article.
Pharmacologically targeting KRAS G12D in PDAC models: tumor cell intrinsic and extrinsic impact.
Kumarasamy V, Frangou C, Wang J, Wan Y, Dynka A, Rosenheck H, Dey P, Abel EV, Knudsen ES, Witkiewicz AK.
Kumarasamy V, et al. Among authors: rosenheck h.
bioRxiv [Preprint]. 2023 Apr 20:2023.03.18.533261. doi: 10.1101/2023.03.18.533261.
bioRxiv. 2023.
PMID: 37162905
Free PMC article.
Preprint.
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Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation.
Mohammadpour H, Tsuji T, MacDonald CR, Sarow JL, Rosenheck H, Daneshmandi S, Choi JE, Qiu J, Matsuzaki J, Witkiewicz AK, Attwood K, Blazar BR, Odunsi K, Repasky EA, McCarthy PL.
Mohammadpour H, et al. Among authors: rosenheck h.
Cell Rep. 2023 Mar 28;42(3):112250. doi: 10.1016/j.celrep.2023.112250. Epub 2023 Mar 15.
Cell Rep. 2023.
PMID: 36924493
Free PMC article.
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RB loss determines selective resistance and novel vulnerabilities in ER-positive breast cancer models.
Kumarasamy V, Nambiar R, Wang J, Rosenheck H, Witkiewicz AK, Knudsen ES.
Kumarasamy V, et al. Among authors: rosenheck h.
Oncogene. 2022 Jul;41(27):3524-3538. doi: 10.1038/s41388-022-02362-2. Epub 2022 Jun 9.
Oncogene. 2022.
PMID: 35676324
Free PMC article.
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CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities.
Knudsen ES, Kumarasamy V, Nambiar R, Pearson JD, Vail P, Rosenheck H, Wang J, Eng K, Bremner R, Schramek D, Rubin SM, Welm AL, Witkiewicz AK.
Knudsen ES, et al. Among authors: rosenheck h.
Cell Rep. 2022 Mar 1;38(9):110448. doi: 10.1016/j.celrep.2022.110448.
Cell Rep. 2022.
PMID: 35235778
Free PMC article.
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Phase Ib/II Study of Cetuximab plus Pembrolizumab in Patients with Advanced RAS Wild-Type Colorectal Cancer.
Fountzilas C, Bajor DL, Mukherjee S, Saltzman J, Witkiewicz AK, Maguire O, Minderman H, Nambiar R, Rosenheck HR, Knudsen ES, Muhitch JB, Abrams SI, Wang C, Hutson AD, Attwood K, Hicks KA, Jurcevic JA, Kalinski P, Iyer R, Boland PM.
Fountzilas C, et al. Among authors: rosenheck hr.
Clin Cancer Res. 2021 Dec 15;27(24):6726-6736. doi: 10.1158/1078-0432.CCR-21-1650. Epub 2021 Oct 13.
Clin Cancer Res. 2021.
PMID: 34645646
Free PMC article.
Clinical Trial.
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