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Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.
Ahlqvist E, Storm P, Käräjämäki A, Martinell M, Dorkhan M, Carlsson A, Vikman P, Prasad RB, Aly DM, Almgren P, Wessman Y, Shaat N, Spégel P, Mulder H, Lindholm E, Melander O, Hansson O, Malmqvist U, Lernmark Å, Lahti K, Forsén T, Tuomi T, Rosengren AH, Groop L. Ahlqvist E, et al. Among authors: rosengren ah. Lancet Diabetes Endocrinol. 2018 May;6(5):361-369. doi: 10.1016/S2213-8587(18)30051-2. Epub 2018 Mar 5. Lancet Diabetes Endocrinol. 2018. PMID: 29503172
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.
Rosengren AH, Jokubka R, Tojjar D, Granhall C, Hansson O, Li DQ, Nagaraj V, Reinbothe TM, Tuncel J, Eliasson L, Groop L, Rorsman P, Salehi A, Lyssenko V, Luthman H, Renström E. Rosengren AH, et al. Science. 2010 Jan 8;327(5962):217-20. doi: 10.1126/science.1176827. Epub 2009 Nov 19. Science. 2010. PMID: 19965390
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.
Rosengren AH, Braun M, Mahdi T, Andersson SA, Travers ME, Shigeto M, Zhang E, Almgren P, Ladenvall C, Axelsson AS, Edlund A, Pedersen MG, Jonsson A, Ramracheya R, Tang Y, Walker JN, Barrett A, Johnson PR, Lyssenko V, McCarthy MI, Groop L, Salehi A, Gloyn AL, Renström E, Rorsman P, Eliasson L. Rosengren AH, et al. Diabetes. 2012 Jul;61(7):1726-33. doi: 10.2337/db11-1516. Epub 2012 Apr 9. Diabetes. 2012. PMID: 22492527 Free PMC article.
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
Taneera J, Lang S, Sharma A, Fadista J, Zhou Y, Ahlqvist E, Jonsson A, Lyssenko V, Vikman P, Hansson O, Parikh H, Korsgren O, Soni A, Krus U, Zhang E, Jing XJ, Esguerra JL, Wollheim CB, Salehi A, Rosengren A, Renström E, Groop L. Taneera J, et al. Cell Metab. 2012 Jul 3;16(1):122-34. doi: 10.1016/j.cmet.2012.06.006. Cell Metab. 2012. PMID: 22768844 Free article.
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH. Mahdi T, et al. Among authors: rosengren ah. Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009. Cell Metab. 2012. PMID: 23140642 Free article.
Can genetics improve precision of therapy in diabetes?
Groop L, Storm P, Rosengren A. Groop L, et al. Trends Endocrinol Metab. 2014 Sep;25(9):440-3. doi: 10.1016/j.tem.2014.06.005. Epub 2014 Jul 11. Trends Endocrinol Metab. 2014. PMID: 25028244
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
Fadista J, Vikman P, Laakso EO, Mollet IG, Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB, Hansson KB, Finotello F, Uvebrant K, Ofori JK, Di Camillo B, Krus U, Cilio CM, Hansson O, Eliasson L, Rosengren AH, Renström E, Wollheim CB, Groop L. Fadista J, et al. Among authors: rosengren ah. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9. doi: 10.1073/pnas.1402665111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201977 Free PMC article.
44 results