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Page 1
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.
Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ. Seldin MM, et al. Among authors: rosenberg gm. Cell Metab. 2018 May 1;27(5):1138-1155.e6. doi: 10.1016/j.cmet.2018.03.015. Cell Metab. 2018. PMID: 29719227 Free PMC article.
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA, Hu CJ, Pan H, Lu J, Abskharon R, Bowler JT, Rosenberg GM, Williams CK, Elezi G, Balbirnie M, Faull KF, Vinters HV, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: rosenberg gm. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2217835120. doi: 10.1073/pnas.2217835120. Epub 2023 Feb 9. Proc Natl Acad Sci U S A. 2023. PMID: 36757890 Free PMC article.
De novo designed protein inhibitors of amyloid aggregation and seeding.
Murray KA, Hu CJ, Griner SL, Pan H, Bowler JT, Abskharon R, Rosenberg GM, Cheng X, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: rosenberg gm. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206240119. doi: 10.1073/pnas.2206240119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969734 Free PMC article.
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: rosenberg gm. bioRxiv [Preprint]. 2021 Mar 18:2021.03.05.434000. doi: 10.1101/2021.03.05.434000. bioRxiv. 2021. PMID: 33688654 Free PMC article. Preprint.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: rosenberg gm. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
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