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Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity.
PLoS One. 2024 Apr 4;19(4):e0295103. doi: 10.1371/journal.pone.0295103. eCollection 2024.
PLoS One. 2024.
PMID: 38574162
Free PMC article.
The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins.
Rosenberg EM Jr, Jian X, Soubias O, Yoon HY, Yadav MP, Hammoudeh S, Pallikkuth S, Akpan I, Chen PW, Maity TK, Jenkins LM, Yohe ME, Byrd RA, Randazzo PA.
Rosenberg EM Jr, et al.
J Biol Chem. 2023 Mar;299(3):102992. doi: 10.1016/j.jbc.2023.102992. Epub 2023 Feb 8.
J Biol Chem. 2023.
PMID: 36758799
Free PMC article.
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The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.
Rosenberg EM Jr, Herrington J, Rajasekaran D, Murphy JW, Pantouris G, Lolis EJ.
Rosenberg EM Jr, et al.
Acta Crystallogr D Struct Biol. 2020 Oct 1;76(Pt 10):1033-1049. doi: 10.1107/S2059798320011687. Epub 2020 Sep 25.
Acta Crystallogr D Struct Biol. 2020.
PMID: 33021505
Free PMC article.
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Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant.
Rosenberg EM Jr, Harrison RES, Tsou LK, Drucker N, Humphries B, Rajasekaran D, Luker KE, Wu CH, Song JS, Wang CJ, Murphy JW, Cheng YC, Shia KS, Luker GD, Morikis D, Lolis EJ.
Rosenberg EM Jr, et al.
Cell Chem Biol. 2019 May 16;26(5):662-673.e7. doi: 10.1016/j.chembiol.2019.01.012. Epub 2019 Feb 28.
Cell Chem Biol. 2019.
PMID: 30827936
Free PMC article.
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An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Pantouris G, Syed MA, Fan C, Rajasekaran D, Cho TY, Rosenberg EM Jr, Bucala R, Bhandari V, Lolis EJ.
Pantouris G, et al. Among authors: rosenberg em jr.
Chem Biol. 2015 Sep 17;22(9):1197-205. doi: 10.1016/j.chembiol.2015.08.006. Epub 2015 Sep 10.
Chem Biol. 2015.
PMID: 26364929
Free PMC article.
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