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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Zhao N, et al. Among authors: rosen jm. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. J Clin Invest. 2018. PMID: 29480818 Free PMC article.
Keratin 6 is not essential for mammary gland development.
Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM. Grimm SL, et al. Among authors: rosen jm. Breast Cancer Res. 2006;8(3):R29. doi: 10.1186/bcr1504. Epub 2006 Jun 21. Breast Cancer Res. 2006. PMID: 16790075 Free PMC article.
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy.
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Li X, et al. J Natl Cancer Inst. 2008 May 7;100(9):672-9. doi: 10.1093/jnci/djn123. Epub 2008 Apr 29. J Natl Cancer Inst. 2008. PMID: 18445819
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features.
Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, Pavlick A, Gutierrez MC, Renshaw L, Larionov AA, Faratian D, Hilsenbeck SG, Perou CM, Lewis MT, Rosen JM, Chang JC. Creighton CJ, et al. Among authors: rosen jm. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13820-5. doi: 10.1073/pnas.0905718106. Epub 2009 Aug 3. Proc Natl Acad Sci U S A. 2009. PMID: 19666588 Free PMC article.
Separation by cell size enriches for mammary stem cell repopulation activity.
Machado HL, Kittrell FS, Edwards D, White AN, Atkinson RL, Rosen JM, Medina D, Lewis MT. Machado HL, et al. Among authors: rosen jm. Stem Cells Transl Med. 2013 Mar;2(3):199-203. doi: 10.5966/sctm.2012-0121. Epub 2013 Feb 13. Stem Cells Transl Med. 2013. PMID: 23408103 Free PMC article.
429 results