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Blocking FSH induces thermogenic adipose tissue and reduces body fat.
Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, Robinson ST, Yu YE, Zhang X, Yang F, Lu P, Zhou Y, Zhu LL, Oberlin DJ, Davies TF, Reagan MR, Brown A, Kumar TR, Epstein S, Iqbal J, Avadhani NG, New MI, Molina H, van Klinken JB, Guo EX, Buettner C, Haider S, Bian Z, Sun L, Rosen CJ, Zaidi M. Liu P, et al. Among authors: rosen cj. Nature. 2017 Jun 1;546(7656):107-112. doi: 10.1038/nature22342. Epub 2017 May 24. Nature. 2017. PMID: 28538730 Free PMC article.
Epitope-specific monoclonal antibodies to FSHβ increase bone mass.
Ji Y, Liu P, Yuen T, Haider S, He J, Romero R, Chen H, Bloch M, Kim SM, Lizneva D, Munshi L, Zhou C, Lu P, Iqbal J, Cheng Z, New MI, Hsueh AJ, Bian Z, Rosen CJ, Sun L, Zaidi M. Ji Y, et al. Among authors: rosen cj. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2192-2197. doi: 10.1073/pnas.1718144115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440419 Free PMC article.
Actions of pituitary hormones beyond traditional targets.
Zaidi M, New MI, Blair HC, Zallone A, Baliram R, Davies TF, Cardozo C, Iqbal J, Sun L, Rosen CJ, Yuen T. Zaidi M, et al. Among authors: rosen cj. J Endocrinol. 2018 Jun;237(3):R83-R98. doi: 10.1530/JOE-17-0680. Epub 2018 Mar 19. J Endocrinol. 2018. PMID: 29555849 Free PMC article. Review.
Regulation of Skeletal Homeostasis.
Zaidi M, Yuen T, Sun L, Rosen CJ. Zaidi M, et al. Among authors: rosen cj. Endocr Rev. 2018 Oct 1;39(5):701-718. doi: 10.1210/er.2018-00050. Endocr Rev. 2018. PMID: 29897433 Free PMC article. Review.
FSH, Bone Mass, Body Fat, and Biological Aging.
Zaidi M, Lizneva D, Kim SM, Sun L, Iqbal J, New MI, Rosen CJ, Yuen T. Zaidi M, et al. Among authors: rosen cj. Endocrinology. 2018 Oct 1;159(10):3503-3514. doi: 10.1210/en.2018-00601. Endocrinology. 2018. PMID: 30085049 Free PMC article.
First-in-class humanized FSH blocking antibody targets bone and fat.
Gera S, Sant D, Haider S, Korkmaz F, Kuo TC, Mathew M, Perez-Pena H, Xie H, Chen H, Batista R, Ma K, Cheng Z, Hadelia E, Robinson C, Macdonald A, Miyashita S, Williams A, Jebian G, Miyashita H, Gumerova A, Ievleva K, Smith P, He J, Ryu V, DeMambro V, Quinn MA, Meseck M, Kim SM, Kumar TR, Iqbal J, New MI, Lizneva D, Rosen CJ, Hsueh AJ, Yuen T, Zaidi M. Gera S, et al. Among authors: rosen cj. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28971-28979. doi: 10.1073/pnas.2014588117. Epub 2020 Oct 30. Proc Natl Acad Sci U S A. 2020. PMID: 33127753 Free PMC article.
618 results