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Blocking FSH induces thermogenic adipose tissue and reduces body fat.
Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, Robinson ST, Yu YE, Zhang X, Yang F, Lu P, Zhou Y, Zhu LL, Oberlin DJ, Davies TF, Reagan MR, Brown A, Kumar TR, Epstein S, Iqbal J, Avadhani NG, New MI, Molina H, van Klinken JB, Guo EX, Buettner C, Haider S, Bian Z, Sun L, Rosen CJ, Zaidi M. Liu P, et al. Among authors: rosen cj. Nature. 2017 Jun 1;546(7656):107-112. doi: 10.1038/nature22342. Epub 2017 May 24. Nature. 2017. PMID: 28538730 Free PMC article.
PPARG by dietary fat interaction influences bone mass in mice and humans.
Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ. Ackert-Bicknell CL, et al. Among authors: rosen cj. J Bone Miner Res. 2008 Sep;23(9):1398-408. doi: 10.1359/jbmr.080419. J Bone Miner Res. 2008. PMID: 18707223 Free PMC article.
Fat targets for skeletal health.
Kawai M, Devlin MJ, Rosen CJ. Kawai M, et al. Among authors: rosen cj. Nat Rev Rheumatol. 2009 Jul;5(7):365-72. doi: 10.1038/nrrheum.2009.102. Epub 2009 May 26. Nat Rev Rheumatol. 2009. PMID: 19468288 Free PMC article. Review.
Emerging therapeutic opportunities for skeletal restoration.
Kawai M, Mödder UI, Khosla S, Rosen CJ. Kawai M, et al. Among authors: rosen cj. Nat Rev Drug Discov. 2011 Feb;10(2):141-56. doi: 10.1038/nrd3299. Nat Rev Drug Discov. 2011. PMID: 21283108 Free PMC article. Review.
A high-fat diet induces bone loss in mice lacking the Alox5 gene.
Le P, Kawai M, Bornstein S, DeMambro VE, Horowitz MC, Rosen CJ. Le P, et al. Among authors: rosen cj. Endocrinology. 2012 Jan;153(1):6-16. doi: 10.1210/en.2011-0082. Epub 2011 Nov 29. Endocrinology. 2012. PMID: 22128029 Free PMC article.
618 results