Rose-John S - Search Results

1

IL-6 trans-signaling in the brain influences the behavioral and physio-pathological phenotype of the Tg2576 and 3xTgAD mouse models of Alzheimer's disease.

Escrig A, Canal C, Sanchis P, Fernández-Gayol O, Montilla A, Comes G, Molinero A, Giralt M, Giménez-Llort L, Becker-Pauly C, Rose-John S, Hidalgo J. Escrig A, et al. Brain Behav Immun. 2019 Nov;82:145-159. doi: 10.1016/j.bbi.2019.08.005. Epub 2019 Aug 8. Brain Behav Immun. 2019. PMID: 31401302

2

IL-6 trans-signaling: the heat is on.

Rose-John S, Neurath MF. Rose-John S, et al. Immunity. 2004 Jan;20(1):2-4. doi: 10.1016/s1074-7613(04)00003-2. Immunity. 2004. PMID: 14738759 Free article.

3

TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

Becker C, Fantini MC, Schramm C, Lehr HA, Wirtz S, Nikolaev A, Burg J, Strand S, Kiesslich R, Huber S, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Galle PR, Blessing M, Rose-John S, Neurath MF. Becker C, et al. Immunity. 2004 Oct;21(4):491-501. doi: 10.1016/j.immuni.2004.07.020. Immunity. 2004. PMID: 15485627 Free article.

4

Impaired hippocampus-dependent and -independent learning in IL-6 deficient mice.

Baier PC, May U, Scheller J, Rose-John S, Schiffelholz T. Baier PC, et al. Behav Brain Res. 2009 Jun 8;200(1):192-6. doi: 10.1016/j.bbr.2009.01.013. Behav Brain Res. 2009. PMID: 19378383

5

Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding.

Garbers C, Jänner N, Chalaris A, Moss ML, Floss DM, Meyer D, Koch-Nolte F, Rose-John S, Scheller J. Garbers C, et al. J Biol Chem. 2011 Apr 29;286(17):14804-11. doi: 10.1074/jbc.M111.229393. Epub 2011 Mar 15. J Biol Chem. 2011. PMID: 21454673 Free PMC article.

6

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.

Jefferson T, Auf dem Keller U, Bellac C, Metz VV, Broder C, Hedrich J, Ohler A, Maier W, Magdolen V, Sterchi E, Bond JS, Jayakumar A, Traupe H, Chalaris A, Rose-John S, Pietrzik CU, Postina R, Overall CM, Becker-Pauly C. Jefferson T, et al. Cell Mol Life Sci. 2013 Jan;70(2):309-33. doi: 10.1007/s00018-012-1106-2. Epub 2012 Sep 1. Cell Mol Life Sci. 2013. PMID: 22940918 Free PMC article.

7

IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.

Rose-John S. Rose-John S. Int J Biol Sci. 2012;8(9):1237-47. doi: 10.7150/ijbs.4989. Epub 2012 Oct 24. Int J Biol Sci. 2012. PMID: 23136552 Free PMC article. Review.

8

Effects of blockade of peripheral interleukin-6 trans-signaling on hippocampus-dependent and independent memory in mice.

Braun O, Dewitz C, Möller-Hackbarth K, Scheller J, Schiffelholz T, Baier PC, Rose-John S. Braun O, et al. J Interferon Cytokine Res. 2013 May;33(5):254-60. doi: 10.1089/jir.2012.0096. Epub 2012 Dec 7. J Interferon Cytokine Res. 2013. PMID: 23215755

9

TNFα cleavage beyond TACE/ADAM17: matrix metalloproteinase 13 is a potential therapeutic target in sepsis and colitis.

Becker-Pauly C, Rose-John S. Becker-Pauly C, et al. EMBO Mol Med. 2013 Jul;5(7):970-2. doi: 10.1002/emmm.201302899. Epub 2013 Jun 11. EMBO Mol Med. 2013. PMID: 23757215 Free PMC article. No abstract available.

10

Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.

Schwarz J, Broder C, Helmstetter A, Schmidt S, Yan I, Müller M, Schmidt-Arras D, Becker-Pauly C, Koch-Nolte F, Mittrücker HW, Rabe B, Rose-John S, Chalaris A. Schwarz J, et al. Biochim Biophys Acta. 2013 Dec;1833(12):3355-3367. doi: 10.1016/j.bbamcr.2013.10.005. Epub 2013 Oct 14. Biochim Biophys Acta. 2013. PMID: 24135057 Free article.

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