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HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin.
Biondini M, Kiepas A, El-Houjeiri L, Annis MG, Hsu BE, Fortier AM, Morin G, Martina JA, Sirois I, Aguilar-Mahecha A, Gruosso T, McGuirk S, Rose AAN, Tokat UM, Johnson RM, Sahin O, Bareke E, St-Pierre J, Park M, Basik M, Majewski J, Puertollano R, Pause A, Huang S, Keler T, Siegel PM. Biondini M, et al. Among authors: rose aan. Oncogene. 2022 Mar;41(12):1701-1717. doi: 10.1038/s41388-022-02206-z. Epub 2022 Feb 2. Oncogene. 2022. PMID: 35110681
Osteoactivin promotes breast cancer metastasis to bone.
Rose AA, Pepin F, Russo C, Abou Khalil JE, Hallett M, Siegel PM. Rose AA, et al. Mol Cancer Res. 2007 Oct;5(10):1001-14. doi: 10.1158/1541-7786.MCR-07-0119. Mol Cancer Res. 2007. PMID: 17951401
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