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Page 1
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS. Yun SP, et al. Among authors: roschke vv. Nat Med. 2018 Jul;24(7):931-938. doi: 10.1038/s41591-018-0051-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892066 Free PMC article.
Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma.
Park JS, Oh Y, Park YJ, Park O, Yang H, Slania S, Hummers LK, Shah AA, An HT, Jang J, Horton MR, Shin J, Dietz HC, Song E, Na DH, Park EJ, Kim K, Lee KC, Roschke VV, Hanes J, Pomper MG, Lee S. Park JS, et al. Among authors: roschke vv. Nat Commun. 2019 Mar 8;10(1):1128. doi: 10.1038/s41467-019-09101-4. Nat Commun. 2019. PMID: 30850660 Free PMC article.
TIP, a T-cell factor identified using high-throughput screening increases survival in a graft-versus-host disease model.
Fiscella M, Perry JW, Teng B, Bloom M, Zhang C, Leung K, Pukac L, Florence K, Concepcion A, Liu B, Meng Y, Chen C, Elgin EC, Kanakaraj P, Kaufmann TE, Porter J, Cibotti R, Mei Y, Zhou J, Chen G, Roschke V, Komatsoulis G, Mansfield B, Ruben S, Sanyal I, Migone TS. Fiscella M, et al. Nat Biotechnol. 2003 Mar;21(3):302-7. doi: 10.1038/nbt797. Epub 2003 Feb 24. Nat Biotechnol. 2003. PMID: 12598909
Synthesis and release of B-lymphocyte stimulator from myeloid cells.
Nardelli B, Belvedere O, Roschke V, Moore PA, Olsen HS, Migone TS, Sosnovtseva S, Carrell JA, Feng P, Giri JG, Hilbert DM. Nardelli B, et al. Blood. 2001 Jan 1;97(1):198-204. doi: 10.1182/blood.v97.1.198. Blood. 2001. PMID: 11133761 Free article.
BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, Giri J, Roschke V, Nardelli B, Carrell J, Sosnovtseva S, Greenfield W, Ruben SM, Olsen HS, Fikes J, Hilbert DM. Moore PA, et al. Science. 1999 Jul 9;285(5425):260-3. doi: 10.1126/science.285.5425.260. Science. 1999. PMID: 10398604
Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.
Kanakaraj P, Puffer BA, Yao XT, Kankanala S, Boyd E, Shah RR, Wang G, Patel D, Krishnamurthy R, Kaithamana S, Smith RG, LaFleur DW, Barbas CF 3rd, Hilbert DM, Kiener PA, Roschke VV. Kanakaraj P, et al. Among authors: roschke vv. MAbs. 2012 Sep-Oct;4(5):600-13. doi: 10.4161/mabs.21227. Epub 2012 Aug 6. MAbs. 2012. PMID: 22864384 Free PMC article.
Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.
Baker KP, Edwards BM, Main SH, Choi GH, Wager RE, Halpern WG, Lappin PB, Riccobene T, Abramian D, Sekut L, Sturm B, Poortman C, Minter RR, Dobson CL, Williams E, Carmen S, Smith R, Roschke V, Hilbert DM, Vaughan TJ, Albert VR. Baker KP, et al. Arthritis Rheum. 2003 Nov;48(11):3253-65. doi: 10.1002/art.11299. Arthritis Rheum. 2003. PMID: 14613291 Free article.
Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.
LaFleur DW, Abramyan D, Kanakaraj P, Smith RG, Shah RR, Wang G, Yao XT, Kankanala S, Boyd E, Zaritskaya L, Nam V, Puffer BA, Buasen P, Kaithamana S, Burnette AF, Krishnamurthy R, Patel D, Roschke VV, Kiener PA, Hilbert DM, Barbas CF 3rd. LaFleur DW, et al. Among authors: roschke vv. MAbs. 2013 Mar-Apr;5(2):208-18. doi: 10.4161/mabs.23043. MAbs. 2013. PMID: 23575268 Free PMC article.
30 results