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Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.
Biochem J. 2021 Jan 15;478(1):1-20. doi: 10.1042/BCJ20200331.
Biochem J. 2021.
PMID: 33305808
Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase.
Purroy R, Medina-Carbonero M, Ros J, Tamarit J.
Purroy R, et al.
Redox Biol. 2020 May;32:101520. doi: 10.1016/j.redox.2020.101520. Epub 2020 Apr 5.
Redox Biol. 2020.
PMID: 32279039
Free PMC article.
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Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon?
Alsina D, Purroy R, Ros J, Tamarit J.
Alsina D, et al. Among authors: purroy r.
Pharmaceuticals (Basel). 2018 Sep 19;11(3):89. doi: 10.3390/ph11030089.
Pharmaceuticals (Basel). 2018.
PMID: 30235822
Free PMC article.
Review.
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Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes.
Pushparaj C, Das A, Purroy R, Nàger M, Herreros J, Pamplona R, Cantí C.
Pushparaj C, et al. Among authors: purroy r.
Int J Biochem Cell Biol. 2015 Nov;68:166-75. doi: 10.1016/j.biocel.2015.09.010. Epub 2015 Sep 30.
Int J Biochem Cell Biol. 2015.
PMID: 26429067
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