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PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves.
Díaz Acosta CC, Dias AA, Rosa TLSA, Batista-Silva LR, Rosa PS, Toledo-Pinto TG, Costa FDMR, Lara FA, Rodrigues LS, Mattos KA, Sarno EN, Bozza PT, Guilhot C, de Berrêdo-Pinho M, Pessolani MCV. Díaz Acosta CC, et al. Among authors: rosa ps, rosa tlsa. PLoS Pathog. 2018 Jul 6;14(7):e1007151. doi: 10.1371/journal.ppat.1007151. eCollection 2018 Jul. PLoS Pathog. 2018. PMID: 29979790 Free PMC article.
Gene expression profiling specifies chemokine, mitochondrial and lipid metabolism signatures in leprosy.
Guerreiro LT, Robottom-Ferreira AB, Ribeiro-Alves M, Toledo-Pinto TG, Rosa Brito T, Rosa PS, Sandoval FG, Jardim MR, Antunes SG, Shannon EJ, Sarno EN, Pessolani MC, Williams DL, Moraes MO. Guerreiro LT, et al. Among authors: rosa ps, rosa brito t. PLoS One. 2013 Jun 14;8(6):e64748. doi: 10.1371/journal.pone.0064748. Print 2013. PLoS One. 2013. PMID: 23798993 Free PMC article.
Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment.
Mattos KA, Oliveira VC, Berrêdo-Pinho M, Amaral JJ, Antunes LC, Melo RC, Acosta CC, Moura DF, Olmo R, Han J, Rosa PS, Almeida PE, Finlay BB, Borchers CH, Sarno EN, Bozza PT, Atella GC, Pessolani MC. Mattos KA, et al. Among authors: rosa ps. Cell Microbiol. 2014 Jun;16(6):797-815. doi: 10.1111/cmi.12279. Epub 2014 Mar 21. Cell Microbiol. 2014. PMID: 24552180 Free PMC article.
Statins increase rifampin mycobactericidal effect.
Lobato LS, Rosa PS, Ferreira Jda S, Neumann Ada S, da Silva MG, do Nascimento DC, Soares CT, Pedrini SC, Oliveira DS, Monteiro CP, Pereira GM, Ribeiro-Alves M, Hacker MA, Moraes MO, Pessolani MC, Duarte RS, Lara FA. Lobato LS, et al. Among authors: rosa ps. Antimicrob Agents Chemother. 2014 Oct;58(10):5766-74. doi: 10.1128/AAC.01826-13. Epub 2014 Jul 21. Antimicrob Agents Chemother. 2014. PMID: 25049257 Free PMC article.
Pre-miR-146a (rs2910164 G>C) single nucleotide polymorphism is genetically and functionally associated with leprosy.
Cezar-de-Mello PF, Toledo-Pinto TG, Marques CS, Arnez LE, Cardoso CC, Guerreiro LT, Antunes SL, Jardim MM, Covas Cde J, Illaramendi X, Dias-Baptista IM, Rosa PS, Durães SM, Pacheco AG, Ribeiro-Alves M, Sarno EN, Moraes MO. Cezar-de-Mello PF, et al. Among authors: rosa ps. PLoS Negl Trop Dis. 2014 Sep 4;8(9):e3099. doi: 10.1371/journal.pntd.0003099. eCollection 2014 Sep. PLoS Negl Trop Dis. 2014. PMID: 25187983 Free PMC article.
STING-Dependent 2'-5' Oligoadenylate Synthetase-Like Production Is Required for Intracellular Mycobacterium leprae Survival.
de Toledo-Pinto TG, Ferreira AB, Ribeiro-Alves M, Rodrigues LS, Batista-Silva LR, Silva BJ, Lemes RM, Martinez AN, Sandoval FG, Alvarado-Arnez LE, Rosa PS, Shannon EJ, Pessolani MC, Pinheiro RO, Antunes SL, Sarno EN, Lara FA, Williams DL, Ozório Moraes M. de Toledo-Pinto TG, et al. Among authors: rosa ps. J Infect Dis. 2016 Jul 15;214(2):311-20. doi: 10.1093/infdis/jiw144. Epub 2016 May 14. J Infect Dis. 2016. PMID: 27190175
Experimental Infection of Rhodnius prolixus (Hemiptera, Triatominae) with Mycobacterium leprae Indicates Potential for Leprosy Transmission.
Neumann Ada S, Dias Fde A, Ferreira Jda S, Fontes AN, Rosa PS, Macedo RE, Oliveira JH, Teixeira RL, Pessolani MC, Moraes MO, Suffys PN, Oliveira PL, Sorgine MH, Lara FA. Neumann Ada S, et al. Among authors: rosa ps. PLoS One. 2016 May 20;11(5):e0156037. doi: 10.1371/journal.pone.0156037. eCollection 2016. PLoS One. 2016. PMID: 27203082 Free PMC article.
Subversion of Schwann Cell Glucose Metabolism by Mycobacterium leprae.
Medeiros RC, Girardi KD, Cardoso FK, Mietto BS, Pinto TG, Gomez LS, Rodrigues LS, Gandini M, Amaral JJ, Antunes SL, Corte-Real S, Rosa PS, Pessolani MC, Nery JA, Sarno EN, Batista-Silva LR, Sola-Penna M, Oliveira MF, Moraes MO, Lara FA. Medeiros RC, et al. Among authors: rosa ps. J Biol Chem. 2016 Oct 7;291(41):21375-21387. doi: 10.1074/jbc.M116.725283. Epub 2016 Aug 23. J Biol Chem. 2016. PMID: 27555322 Free PMC article.
Subversion of Schwann cell glucose metabolism by Mycobacterium leprae.
Medeiros RCA, Girardi KDCV, Cardoso FKL, Mietto BS, Pinto TGT, Gomez LS, Rodrigues LS, Gandini M, Amaral JJ, Antunes SLG, Corte-Real S, Rosa PS, Pessolani MCV, Nery JADC, Sarno EN, Batista-Silva LR, Sola-Penna M, de Oliveira MF, Moraes MO, Lara FA. Medeiros RCA, et al. Among authors: rosa ps. J Biol Chem. 2016 Nov 18;291(47):24803. doi: 10.1074/jbc.A116.725283. J Biol Chem. 2016. PMID: 27864529 Free PMC article. No abstract available.
106 results