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Page 1
Antiparasitic activity of nerolidol in a mouse model of schistosomiasis.
Silva MP, de Oliveira RN, Mengarda AC, Roquini DB, Allegretti SM, Salvadori MC, Teixeira FS, de Sousa DP, Pinto PLS, da Silva Filho AA, de Moraes J. Silva MP, et al. Among authors: roquini db. Int J Antimicrob Agents. 2017 Sep;50(3):467-472. doi: 10.1016/j.ijantimicag.2017.06.005. Epub 2017 Jun 27. Int J Antimicrob Agents. 2017. PMID: 28666754
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.
Guimarães MA, de Oliveira RN, de Almeida RL, Mafud AC, Sarkis ALV, Ganassin R, da Silva MP, Roquini DB, Veras LM, Sawada TCH, Ropke CD, Muehlmann LA, Joanitti GA, Kuckelhaus SAS, Allegretti SM, Mascarenhas YP, de Moraes J, Leite JRSA. Guimarães MA, et al. Among authors: roquini db. PLoS One. 2018 May 11;13(5):e0196667. doi: 10.1371/journal.pone.0196667. eCollection 2018. PLoS One. 2018. PMID: 29750792 Free PMC article.
Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model.
Roquini DB, Cogo RM, Mengarda AC, Mazloum SF, Morais CS, Xavier RP, Salvadori MC, Teixeira FS, Ferreira LE, Pinto PL, Morais TR, de Moraes J. Roquini DB, et al. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01208-19. doi: 10.1128/AAC.01208-19. Epub 2019 Sep 16. Antimicrob Agents Chemother. 2019. PMID: 31527034 Free PMC article.
H1-antihistamines as antischistosomal drugs: in vitro and in vivo studies.
Xavier RP, Mengarda AC, Silva MP, Roquini DB, Salvadori MC, Teixeira FS, Pinto PL, Morais TR, Ferreira LLG, Andricopulo AD, de Moraes J. Xavier RP, et al. Among authors: roquini db. Parasit Vectors. 2020 Jun 1;13(1):278. doi: 10.1186/s13071-020-04140-z. Parasit Vectors. 2020. PMID: 32487175 Free PMC article.
Enhancing the antischistosomal activity of carvacryl acetate using nanoemulsion.
de Souza RL, Mengarda AC, Roquini DB, Melo CO, de Morais MC, C Espírito-Santo MC, de Sousa DP, Moraes J, Oliveira EE. de Souza RL, et al. Among authors: roquini db. Nanomedicine (Lond). 2023 Feb;18(4):331-342. doi: 10.2217/nnm-2022-0228. Epub 2023 May 4. Nanomedicine (Lond). 2023. PMID: 37140262