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185 results

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Page 1
Hypothalamic S1P/S1PR1 axis controls energy homeostasis.
Silva VR, Micheletti TO, Pimentel GD, Katashima CK, Lenhare L, Morari J, Mendes MC, Razolli DS, Rocha GZ, de Souza CT, Ryu D, Prada PO, Velloso LA, Carvalheira JB, Pauli JR, Cintra DE, Ropelle ER. Silva VR, et al. Among authors: ropelle er. Nat Commun. 2014 Sep 25;5:4859. doi: 10.1038/ncomms5859. Nat Commun. 2014. PMID: 25255053 Free article.
Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.
van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P. van de Weijer T, et al. Among authors: ropelle er. Diabetes. 2015 Apr;64(4):1193-201. doi: 10.2337/db14-0667. Epub 2014 Oct 28. Diabetes. 2015. PMID: 25352640 Free PMC article. Clinical Trial.
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.
Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku CS, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J. Gariani K, et al. Among authors: ropelle er. Hepatology. 2016 Apr;63(4):1190-204. doi: 10.1002/hep.28245. Epub 2015 Dec 16. Hepatology. 2016. PMID: 26404765 Free PMC article.
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.
Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J. Ryu D, et al. Among authors: ropelle er. Sci Transl Med. 2016 Oct 19;8(361):361ra139. doi: 10.1126/scitranslmed.aaf5504. Sci Transl Med. 2016. PMID: 27798264 Free PMC article.
NAD+ precursor increases aerobic performance in mice.
Crisol BM, Veiga CB, Braga RR, Lenhare L, Baptista IL, Gaspar RC, Muñoz VR, Cordeiro AV, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER. Crisol BM, et al. Among authors: ropelle er. Eur J Nutr. 2020 Sep;59(6):2427-2437. doi: 10.1007/s00394-019-02089-z. Epub 2019 Sep 7. Eur J Nutr. 2020. PMID: 31494696
Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice.
Ropelle ER, Pauli JR, Cintra DE, da Silva AS, De Souza CT, Guadagnini D, Carvalho BM, Caricilli AM, Katashima CK, Carvalho-Filho MA, Hirabara S, Curi R, Velloso LA, Saad MJ, Carvalheira JB. Ropelle ER, et al. Diabetes. 2013 Feb;62(2):466-70. doi: 10.2337/db12-0339. Epub 2012 Sep 18. Diabetes. 2013. PMID: 22991447 Free PMC article.
Nicotinamide riboside induces a thermogenic response in lean mice.
Crisol BM, Veiga CB, Lenhare L, Braga RR, Silva VRR, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER. Crisol BM, et al. Among authors: ropelle er. Life Sci. 2018 Oct 15;211:1-7. doi: 10.1016/j.lfs.2018.09.015. Epub 2018 Sep 6. Life Sci. 2018. PMID: 30195617
Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice.
Cordeiro AV, Brícola RS, Braga RR, Lenhare L, Silva VRR, Anaruma CP, Katashima CK, Crisol BM, Simabuco FM, Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER. Cordeiro AV, et al. Among authors: ropelle er. J Gerontol A Biol Sci Med Sci. 2020 Nov 13;75(12):2258-2261. doi: 10.1093/gerona/glaa059. J Gerontol A Biol Sci Med Sci. 2020. PMID: 32173728
High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice.
Cordeiro AV, Peruca GF, Braga RR, Brícola RS, Lenhare L, Silva VRR, Anaruma CP, Katashima CK, Crisol BM, Barbosa LT, Simabuco FM, da Silva ASR, Cintra DE, de Moura LP, Pauli JR, Ropelle ER. Cordeiro AV, et al. Among authors: ropelle er. Geroscience. 2021 Jun;43(3):1513-1518. doi: 10.1007/s11357-020-00246-5. Epub 2020 Jul 31. Geroscience. 2021. PMID: 32737758 Free PMC article.
185 results