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Page 1
Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.
Ronzaud C, Loffing-Cueni D, Hausel P, Debonneville A, Malsure SR, Fowler-Jaeger N, Boase NA, Perrier R, Maillard M, Yang B, Stokes JB, Koesters R, Kumar S, Hummler E, Loffing J, Staub O. Ronzaud C, et al. J Clin Invest. 2013 Feb;123(2):657-65. doi: 10.1172/JCI61110. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348737 Free PMC article.
Sodium and potassium balance depends on αENaC expression in connecting tubule.
Christensen BM, Perrier R, Wang Q, Zuber AM, Maillard M, Mordasini D, Malsure S, Ronzaud C, Stehle JC, Rossier BC, Hummler E. Christensen BM, et al. Among authors: ronzaud c. J Am Soc Nephrol. 2010 Nov;21(11):1942-51. doi: 10.1681/ASN.2009101077. Epub 2010 Oct 14. J Am Soc Nephrol. 2010. PMID: 20947633 Free PMC article.
Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.
Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O. Arroyo JP, et al. Among authors: ronzaud c. J Am Soc Nephrol. 2011 Sep;22(9):1707-19. doi: 10.1681/ASN.2011020132. Epub 2011 Aug 18. J Am Soc Nephrol. 2011. PMID: 21852580 Free PMC article.
Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Roy A, Al-Qusairi L, Donnelly BF, Ronzaud C, Marciszyn AL, Gong F, Chang YP, Butterworth MB, Pastor-Soler NM, Hallows KR, Staub O, Subramanya AR. Roy A, et al. Among authors: ronzaud c. J Clin Invest. 2015 Sep;125(9):3433-48. doi: 10.1172/JCI75245. Epub 2015 Aug 4. J Clin Invest. 2015. PMID: 26241057 Free PMC article.