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Dysautonomia due to reduced cholinergic neurotransmission causes cardiac remodeling and heart failure.
Lara A, Damasceno DD, Pires R, Gros R, Gomes ER, Gavioli M, Lima RF, Guimarães D, Lima P, Bueno CR Jr, Vasconcelos A, Roman-Campos D, Menezes CA, Sirvente RA, Salemi VM, Mady C, Caron MG, Ferreira AJ, Brum PC, Resende RR, Cruz JS, Gomez MV, Prado VF, de Almeida AP, Prado MA, Guatimosim S. Lara A, et al. Mol Cell Biol. 2010 Apr;30(7):1746-56. doi: 10.1128/MCB.00996-09. Epub 2010 Feb 1. Mol Cell Biol. 2010. PMID: 20123977 Free PMC article.
Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway.
Cunha TM, Roman-Campos D, Lotufo CM, Duarte HL, Souza GR, Verri WA Jr, Funez MI, Dias QM, Schivo IR, Domingues AC, Sachs D, Chiavegatto S, Teixeira MM, Hothersall JS, Cruz JS, Cunha FQ, Ferreira SH. Cunha TM, et al. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4442-7. doi: 10.1073/pnas.0914733107. Epub 2010 Feb 10. Proc Natl Acad Sci U S A. 2010. PMID: 20147620 Free PMC article.
69 results