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Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - secondary analyses of a randomised, placebo-controlled trial (the AIM study).
Bråten LCH, Grøvle L, Espeland A, Pripp AH, Grotle M, Helllum C, Haugen AJ, Froholdt A, Rolfsen MP, Nygaard ØP, Lutro O, Kristoffersen PM, Anke A, Schistad EI, Skouen JS, Brox JI, Zwart JA, Storheim K; AIM-study group. Bråten LCH, et al. Among authors: rolfsen mp. BMC Musculoskelet Disord. 2020 Jul 13;21(1):458. doi: 10.1186/s12891-020-03422-y. BMC Musculoskelet Disord. 2020. PMID: 32660517 Free PMC article. Clinical Trial.
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial.
Bråten LCH, Rolfsen MP, Espeland A, Wigemyr M, Aßmus J, Froholdt A, Haugen AJ, Marchand GH, Kristoffersen PM, Lutro O, Randen S, Wilhelmsen M, Winsvold BS, Kadar TI, Holmgard TE, Vigeland MD, Vetti N, Nygaard ØP, Lie BA, Hellum C, Anke A, Grotle M, Schistad EI, Skouen JS, Grøvle L, Brox JI, Zwart JA, Storheim K; AIM study group. Bråten LCH, et al. Among authors: rolfsen mp. BMJ. 2019 Oct 16;367:l5654. doi: 10.1136/bmj.l5654. BMJ. 2019. PMID: 31619437 Free PMC article. Clinical Trial.
Short tau inversion recovery MRI of Modic changes: a reliability study.
Kristoffersen PM, Vetti N, Storheim K, Bråten LC, Rolfsen MP, Assmus J, Espeland A. Kristoffersen PM, et al. Among authors: rolfsen mp. Acta Radiol Open. 2020 Jan 29;9(1):2058460120902402. doi: 10.1177/2058460120902402. eCollection 2020 Jan. Acta Radiol Open. 2020. PMID: 32064122 Free PMC article.
Cost-utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study).
Grotle M, Bråten LC, Brox JI, Espeland A, Zolic-Karlsson Z, Munk Killingmo R, Tingulstad A, Grøvle L, Froholdt A, Kristoffersen PM, Wigemyr M, van Tulder MW, Storheim K, Zwart JA; AIM-study group. Grotle M, et al. BMJ Open. 2020 Jun 15;10(6):e035461. doi: 10.1136/bmjopen-2019-035461. BMJ Open. 2020. PMID: 32546490 Free PMC article. Clinical Trial.
Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis.
Austevoll IM, Hermansen E, Fagerland MW, Storheim K, Brox JI, Solberg T, Rekeland F, Franssen E, Weber C, Brisby H, Grundnes O, Algaard KRH, Böker T, Banitalebi H, Indrekvam K, Hellum C; NORDSTEN-DS Investigators. Austevoll IM, et al. N Engl J Med. 2021 Aug 5;385(6):526-538. doi: 10.1056/NEJMoa2100990. N Engl J Med. 2021. PMID: 34347953 Clinical Trial.
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement.
Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Kristoffersen PM, Vetti N, Wigemyr M, Bråten LCH, Gjefsen E, Schistad EI, Haugen AJ, Froholdt A, Skouen JS, Zwart JA, Storheim K, Pedersen LM, Lie BA; AIM Study Group. Vigeland MD, et al. Sci Rep. 2022 Jan 7;12(1):215. doi: 10.1038/s41598-021-04189-5. Sci Rep. 2022. PMID: 34997115 Free PMC article.
Amoxicillin Did Not Reduce Modic Change Edema in Patients With Chronic Low Back Pain: Subgroup Analyses of a Randomised Trial (the AIM Study).
Kristoffersen PM, Vetti N, Grøvle L, Brox JI, Haugli Bråten LC, Grotle M, Julsrud Haugen A, Rolfsen MP, Froholdt A, Skouen JS, Lutro O, Marchand GH, Anke A, Zwart JA, Storheim K, Assmus J, Espeland A. Kristoffersen PM, et al. Among authors: rolfsen mp. Spine (Phila Pa 1976). 2023 Feb 1;48(3):147-154. doi: 10.1097/BRS.0000000000004513. Epub 2022 Oct 12. Spine (Phila Pa 1976). 2023. PMID: 36223435 Free PMC article. Clinical Trial.
Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain.
Espeland A, Kristoffersen PM, Bråten LCH, Grøvle L, Grotle M, Haugen AJ, Rolfsen MP, Hellum C, Zwart JA, Storheim K, Assmus J, Vetti N. Espeland A, et al. Among authors: rolfsen mp. Spine (Phila Pa 1976). 2023 Dec 15;48(24):1699-1708. doi: 10.1097/BRS.0000000000004837. Epub 2023 Sep 27. Spine (Phila Pa 1976). 2023. PMID: 37759351 Free PMC article. Clinical Trial.
Association of Modic change types and their short tau inversion recovery signals with clinical characteristics- a cross sectional study of chronic low back pain patients in the AIM-study.
Bråten LCH, Schistad EI, Espeland A, Kristoffersen PM, Haugen AJ, Marchand GH, Vetti N, Pripp AH, Kadar TI, Skouen JS, Grotle M, Grøvle L, Zwart JA, Brox JI, Storheim K; AIM-study group. Bråten LCH, et al. BMC Musculoskelet Disord. 2020 Jun 10;21(1):368. doi: 10.1186/s12891-020-03381-4. BMC Musculoskelet Disord. 2020. PMID: 32522268 Free PMC article. Clinical Trial.