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Notch signaling inactivation by small molecule γ-secretase inhibitors restores the multiciliated cell population in the airway epithelium.
Vladar EK, Kunimoto K, Rojas-Hernandez LS, Spano JM, Sellers ZM, Joo NS, Cooney RA, Axelrod JD, Milla CE. Vladar EK, et al. Among authors: rojas hernandez ls. Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1;324(6):L771-L782. doi: 10.1152/ajplung.00382.2022. Epub 2023 Apr 11. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37039381 Free PMC article.
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, Milla C, Andino R, Jackson PK. Wu CT, et al. Among authors: rojas hernandez ls. Cell. 2023 Jan 5;186(1):112-130.e20. doi: 10.1016/j.cell.2022.11.030. Epub 2022 Dec 2. Cell. 2023. PMID: 36580912 Free PMC article.