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Accelerated generation of gene-engineered monoclonal CHO cell lines using FluidFM nanoinjection and CRISPR/Cas9.
Biotechnol J. 2024 Apr;19(4):e2300505. doi: 10.1002/biot.202300505.
Biotechnol J. 2024.
PMID: 38651269
CRISPR-Cas9-Based Gene Knockout of Immune Checkpoints in Expanded NK Cells.
Mohammadian Gol T, Kim M, Sinn R, Ureña-Bailén G, Stegmeyer S, Gratz PG, Zahedipour F, Roig-Merino A, Antony JS, Mezger M.
Mohammadian Gol T, et al. Among authors: roig merino a.
Int J Mol Sci. 2023 Nov 8;24(22):16065. doi: 10.3390/ijms242216065.
Int J Mol Sci. 2023.
PMID: 38003255
Free PMC article.
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Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency.
Braun T, Pruene A, Darguzyte M, Vom Stein AF, Nguyen PH, Wagner DL, Kath J, Roig-Merino A, Heuser M, Riehm LL, Schneider A, Awerkiew S, Talbot SR, Bleich A, Figueiredo C, Bornhäuser M, Stripecke R.
Braun T, et al. Among authors: roig merino a.
Front Immunol. 2023 Mar 24;14:1086433. doi: 10.3389/fimmu.2023.1086433. eCollection 2023.
Front Immunol. 2023.
PMID: 37033919
Free PMC article.
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Challenges in Gene Therapy for Somatic Reverted Mosaicism in X-Linked Combined Immunodeficiency by CRISPR/Cas9 and Prime Editing.
Hou Y, Ureña-Bailén G, Mohammadian Gol T, Gratz PG, Gratz HP, Roig-Merino A, Antony JS, Lamsfus-Calle A, Daniel-Moreno A, Handgretinger R, Mezger M.
Hou Y, et al. Among authors: roig merino a.
Genes (Basel). 2022 Dec 13;13(12):2348. doi: 10.3390/genes13122348.
Genes (Basel). 2022.
PMID: 36553615
Free PMC article.
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Preclinical Evaluation of CRISPR-Edited CAR-NK-92 Cells for Off-the-Shelf Treatment of AML and B-ALL.
Ureña-Bailén G, Dobrowolski JM, Hou Y, Dirlam A, Roig-Merino A, Schleicher S, Atar D, Seitz C, Feucht J, Antony JS, Mohammadian Gol T, Handgretinger R, Mezger M.
Ureña-Bailén G, et al. Among authors: roig merino a.
Int J Mol Sci. 2022 Oct 24;23(21):12828. doi: 10.3390/ijms232112828.
Int J Mol Sci. 2022.
PMID: 36361619
Free PMC article.
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An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny.
Roig-Merino A, Urban M, Bozza M, Peterson JD, Bullen L, Büchler-Schäff M, Stäble S, van der Hoeven F, Müller-Decker K, McKay TR, Milsom MD, Harbottle RP.
Roig-Merino A, et al.
Stem Cell Reports. 2022 Jan 11;17(1):143-158. doi: 10.1016/j.stemcr.2021.11.011. Epub 2021 Dec 22.
Stem Cell Reports. 2022.
PMID: 34942088
Free PMC article.
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Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Thornton CD, Fielding S, Karbowniczek K, Roig-Merino A, Burrows AE, FitzPatrick LM, Sharaireh A, Tite JP, Mole SE, Harbottle RP, Caproni LJ, McKay TR.
Thornton CD, et al. Among authors: roig merino a.
Mol Ther Methods Clin Dev. 2021 Oct 5;23:348-358. doi: 10.1016/j.omtm.2021.09.018. eCollection 2021 Dec 10.
Mol Ther Methods Clin Dev. 2021.
PMID: 34729381
Free PMC article.
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