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SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan.
Roichman A, Kanfi Y, Glazz R, Naiman S, Amit U, Landa N, Tinman S, Stein I, Pikarsky E, Leor J, Cohen HY. Roichman A, et al. J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):603-615. doi: 10.1093/gerona/glw152. J Gerontol A Biol Sci Med Sci. 2017. PMID: 27519885
Multiple regulatory layers of SREBP1/2 by SIRT6.
Elhanati S, Kanfi Y, Varvak A, Roichman A, Carmel-Gross I, Barth S, Gibor G, Cohen HY. Elhanati S, et al. Among authors: roichman a. Cell Rep. 2013 Sep 12;4(5):905-12. doi: 10.1016/j.celrep.2013.08.006. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012758 Free article.
Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.
Naiman S, Huynh FK, Gil R, Glick Y, Shahar Y, Touitou N, Nahum L, Avivi MY, Roichman A, Kanfi Y, Gertler AA, Doniger T, Ilkayeva OR, Abramovich I, Yaron O, Lerrer B, Gottlieb E, Harris RA, Gerber D, Hirschey MD, Cohen HY. Naiman S, et al. Among authors: roichman a. Cell Rep. 2019 Dec 17;29(12):4127-4143.e8. doi: 10.1016/j.celrep.2019.11.067. Cell Rep. 2019. PMID: 31851938 Free PMC article.
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V. Simon M, et al. Among authors: roichman a. Cell Metab. 2019 Apr 2;29(4):871-885.e5. doi: 10.1016/j.cmet.2019.02.014. Epub 2019 Mar 7. Cell Metab. 2019. PMID: 30853213 Free PMC article.
L-Lactate Promotes Adult Hippocampal Neurogenesis.
Lev-Vachnish Y, Cadury S, Rotter-Maskowitz A, Feldman N, Roichman A, Illouz T, Varvak A, Nicola R, Madar R, Okun E. Lev-Vachnish Y, et al. Among authors: roichman a. Front Neurosci. 2019 May 24;13:403. doi: 10.3389/fnins.2019.00403. eCollection 2019. Front Neurosci. 2019. PMID: 31178678 Free PMC article.
Telomeres and Longevity: A Cause or an Effect?
Adwan Shekhidem H, Sharvit L, Leman E, Manov I, Roichman A, Holtze S, M Huffman D, Y Cohen H, Bernd Hildebrandt T, Shams I, Atzmon G. Adwan Shekhidem H, et al. Among authors: roichman a. Int J Mol Sci. 2019 Jul 1;20(13):3233. doi: 10.3390/ijms20133233. Int J Mol Sci. 2019. PMID: 31266154 Free PMC article.
14 results