Rohde CM - Search Results

1

A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers.

Mathur D, Root AR, Bugaj-Gaweda B, Bisulco S, Tan X, Fang W, Kearney JC, Lucas J, Guffroy M, Golas J, Rohde CM, Stevens C, Kamperschroer C, Kelleher K, Lawrence-Henderson RF, Upeslacis E, Yao J, Narula J, LaVallie ER, Fernandez DR, Buetow BS, Rosfjord E, Bloom L, King LE, Tchistiakova L, Nguyen A, Sapra P. Mathur D, et al. Among authors: rohde cm. Clin Cancer Res. 2020 May 1;26(9):2188-2202. doi: 10.1158/1078-0432.CCR-19-3275. Epub 2020 Jan 29. Clin Cancer Res. 2020. PMID: 31996389

2

PF-06804103, A Site-specific Anti-HER2 Antibody-Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers.

Graziani EI, Sung M, Ma D, Narayanan B, Marquette K, Puthenveetil S, Tumey LN, Bikker J, Casavant J, Bennett EM, Charati MB, Golas J, Hosselet C, Rohde CM, Hu G, Guffroy M, Falahatpisheh H, Finkelstein M, Clark T, Barletta F, Tchistiakova L, Lucas J, Rosfjord E, Loganzo F, O'Donnell CJ, Gerber HP, Sapra P. Graziani EI, et al. Among authors: rohde cm. Mol Cancer Ther. 2020 Oct;19(10):2068-2078. doi: 10.1158/1535-7163.MCT-20-0237. Epub 2020 Aug 3. Mol Cancer Ther. 2020. PMID: 32747418

3

Inflammatory Cell Findings in the Female Rabbit Heart and Stress-associated Exacerbation with Handling and Procedures Used in Nonclinical Studies.

Sellers RS, Pardo I, Hu G, Khan KN, Perry R, Markiewicz V, Rohde C, Colangelo J, Reagan W, Clarke D. Sellers RS, et al. Toxicol Pathol. 2017 Apr;45(3):416-426. doi: 10.1177/0192623317700519. Epub 2017 Mar 28. Toxicol Pathol. 2017. PMID: 28349785

4

Maternal immunization with Group B Streptococcus six-valent polysaccharide conjugate vaccine supported by lack of toxicity in rat and rabbit fertility and developmental toxicity studies.

Catlin NR, Cappon GD, Engel S, Rohde C, Nowland WS, Buitrago S, Scully I, Anderson AS, Bowman CJ. Catlin NR, et al. Birth Defects Res. 2021 Nov 15;113(19):1343-1356. doi: 10.1002/bdr2.1953. Epub 2021 Sep 13. Birth Defects Res. 2021. PMID: 34516044

5

Activation of TrkB with TAM-163 results in opposite effects on body weight in rodents and non-human primates.

Perreault M, Feng G, Will S, Gareski T, Kubasiak D, Marquette K, Vugmeyster Y, Unger TJ, Jones J, Qadri A, Hahm S, Sun Y, Rohde CM, Zwijnenberg R, Paulsen J, Gimeno RE. Perreault M, et al. Among authors: rohde cm. PLoS One. 2013 May 20;8(5):e62616. doi: 10.1371/journal.pone.0062616. Print 2013. PLoS One. 2013. PMID: 23700410 Free PMC article.

6

Mechanistic investigations of test article-induced pancreatic toxicity at the endocrine-exocrine interface in the rat.

Brenneman KA, Ramaiah SK, Rohde CM, Messing DM, O'Neil SP, Gauthier LM, Stewart ZS, Mantena SR, Shevlin KM, Leonard CG, Sokolowski SA, Lin H, Carraher DC, Jesson MI, Tomlinson L, Zhan Y, Bobrowski WF, Bailey SA, Vogel WM, Morris DL, Whiteley LO, Davis JW 2nd. Brenneman KA, et al. Among authors: rohde cm. Toxicol Pathol. 2014 Jan;42(1):229-42. doi: 10.1177/0192623313508851. Epub 2013 Nov 13. Toxicol Pathol. 2014. PMID: 24226507

7

Lack of effects on female fertility and prenatal and postnatal offspring development in rats with BNT162b2, a mRNA-based COVID-19 vaccine.

Bowman CJ, Bouressam M, Campion SN, Cappon GD, Catlin NR, Cutler MW, Diekmann J, Rohde CM, Sellers RS, Lindemann C. Bowman CJ, et al. Among authors: rohde cm. Reprod Toxicol. 2021 Aug;103:28-35. doi: 10.1016/j.reprotox.2021.05.007. Epub 2021 May 28. Reprod Toxicol. 2021. PMID: 34058573 Free PMC article.

8

Metabonomic evaluation of metabolic dysregulation in rats induced by PF 376304, a novel inhibitor of phosphoinositide 3-kinase.

Robertson DG, Datta K, Wells D, Egnash L, Robosky L, Manning M, Rohde C, Reily MD. Robertson DG, et al. Chem Res Toxicol. 2007 Dec;20(12):1871-7. doi: 10.1021/tx7002036. Epub 2007 Nov 15. Chem Res Toxicol. 2007. PMID: 18001061

9

Agonistic TAM-163 antibody targeting tyrosine kinase receptor-B: applying mechanistic modeling to enable preclinical to clinical translation and guide clinical trial design.

Vugmeyster Y, Rohde C, Perreault M, Gimeno RE, Singh P. Vugmeyster Y, et al. MAbs. 2013 May-Jun;5(3):373-83. doi: 10.4161/mabs.23826. Epub 2013 Mar 25. MAbs. 2013. PMID: 23529133 Free PMC article.

10

COVID-19 Therapeutics and Vaccines: A Race to Save Lives.

Bebenek I, Bannister R, Dubinion J, Fortin M, Liu M, Motter AL, Rohde CM, Wrzesinski C. Bebenek I, et al. Among authors: rohde cm. Toxicol Sci. 2022 Jan 24;185(2):119-127. doi: 10.1093/toxsci/kfab130. Toxicol Sci. 2022. PMID: 34735018

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