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Molecular details of ruthenium red pore block in TRPV channels.
Pumroy RA, De Jesús-Pérez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V. Pumroy RA, et al. Among authors: rohacs t. EMBO Rep. 2024 Feb;25(2):506-523. doi: 10.1038/s44319-023-00050-0. Epub 2024 Jan 15. EMBO Rep. 2024. PMID: 38225355 Free PMC article.
Structural insights on TRPV5 gating by endogenous modulators.
Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY. Hughes TET, et al. Among authors: rohacs t. Nat Commun. 2018 Oct 10;9(1):4198. doi: 10.1038/s41467-018-06753-6. Nat Commun. 2018. PMID: 30305626 Free PMC article.
Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY. Pumroy RA, et al. Among authors: rohacs t. Elife. 2019 Sep 30;8:e48792. doi: 10.7554/eLife.48792. Elife. 2019. PMID: 31566564 Free PMC article.
Structural mechanism of TRPV5 inhibition by econazole.
De Jesús-Pérez JJ, Gabrielle M, Raheem S, Fluck EC, Rohacs T, Moiseenkova-Bell VY. De Jesús-Pérez JJ, et al. Among authors: rohacs t. Structure. 2024 Feb 1;32(2):148-156.e5. doi: 10.1016/j.str.2023.11.012. Epub 2023 Dec 22. Structure. 2024. PMID: 38141613
Structure-based characterization of novel TRPV5 inhibitors.
Hughes TE, Del Rosario JS, Kapoor A, Yazici AT, Yudin Y, Fluck EC 3rd, Filizola M, Rohacs T, Moiseenkova-Bell VY. Hughes TE, et al. Among authors: rohacs t. Elife. 2019 Oct 25;8:e49572. doi: 10.7554/eLife.49572. Elife. 2019. PMID: 31647410 Free PMC article.
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Hughes TET, et al. Among authors: rohacs t. Nat Struct Mol Biol. 2018 Jan;25(1):53-60. doi: 10.1038/s41594-017-0009-1. Epub 2018 Jan 1. Nat Struct Mol Biol. 2018. PMID: 29323279 Free PMC article.
92 results