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Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity.
Bavlovič Piskáčková H, Jansová H, Kubeš J, Karabanovich G, Váňová N, Kollárová-Brázdová P, Melnikova I, Jirkovská A, Lenčová-Popelová O, Chládek J, Roh J, Šimůnek T, Štěrba M, Štěrbová-Kovaříková P. Bavlovič Piskáčková H, et al. Among authors: roh j. Sci Rep. 2021 Feb 24;11(1):4456. doi: 10.1038/s41598-021-83688-x. Sci Rep. 2021. PMID: 33627707 Free PMC article.
Amino acid derivatives as transdermal permeation enhancers.
Janůšová B, Skolová B, Tükörová K, Wojnarová L, Simůnek T, Mladěnka P, Filipský T, Ríha M, Roh J, Palát K, Hrabálek A, Vávrová K. Janůšová B, et al. Among authors: roh j. J Control Release. 2013 Jan 28;165(2):91-100. doi: 10.1016/j.jconrel.2012.11.003. Epub 2012 Nov 12. J Control Release. 2013. PMID: 23154194
Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats.
Stariat J, Suprunová V, Roh J, Šesták V, Eisner T, Filipský T, Mladěnka P, Nobilis M, Šimůnek T, Klimeš J, Kalinowski DS, Richardson DR, Kovaříková P. Stariat J, et al. Among authors: roh j. Biomed Chromatogr. 2014 May;28(5):621-9. doi: 10.1002/bmc.3080. Epub 2013 Nov 20. Biomed Chromatogr. 2014. PMID: 24254882
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria.
Karabanovich G, Roh J, Smutný T, Němeček J, Vicherek P, Stolaříková J, Vejsová M, Dufková I, Vávrová K, Pávek P, Klimešová V, Hrabálek A. Karabanovich G, et al. Among authors: roh j. Eur J Med Chem. 2014 Jul 23;82:324-40. doi: 10.1016/j.ejmech.2014.05.069. Epub 2014 Jun 2. Eur J Med Chem. 2014. PMID: 24927053
In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.
Potůčková E, Roh J, Macháček M, Sahni S, Stariat J, Šesták V, Jansová H, Hašková P, Jirkovská A, Vávrová K, Kovaříková P, Kalinowski DS, Richardson DR, Šimůnek T. Potůčková E, et al. Among authors: roh j. PLoS One. 2015 Oct 13;10(10):e0139929. doi: 10.1371/journal.pone.0139929. eCollection 2015. PLoS One. 2015. PMID: 26460540 Free PMC article.
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.
Sestak V, Stariat J, Cermanova J, Potuckova E, Chladek J, Roh J, Bures J, Jansova H, Prusa P, Sterba M, Micuda S, Simunek T, Kalinowski DS, Richardson DR, Kovarikova P. Sestak V, et al. Among authors: roh j. Oncotarget. 2015 Dec 15;6(40):42411-28. doi: 10.18632/oncotarget.6389. Oncotarget. 2015. PMID: 26623727 Free PMC article.
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Karabanovich G, Zemanová J, Smutný T, Székely R, Šarkan M, Centárová I, Vocat A, Pávková I, Čonka P, Němeček J, Stolaříková J, Vejsová M, Vávrová K, Klimešová V, Hrabálek A, Pávek P, Cole ST, Mikušová K, Roh J. Karabanovich G, et al. Among authors: roh j. J Med Chem. 2016 Mar 24;59(6):2362-80. doi: 10.1021/acs.jmedchem.5b00608. Epub 2016 Mar 15. J Med Chem. 2016. PMID: 26948407
2,038 results