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iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples.
Verheijen MCT, Krauskopf J, Caiment F, Nazaruk M, Wen QF, van Herwijnen MHM, Hauser DA, Gajjar M, Verfaillie C, Vermeiren Y, De Deyn PP, Wittens MMJ, Sieben A, Engelborghs S, Dejonckheere W, Princen K, Griffioen G, Roggen EL, Briedé JJ. Verheijen MCT, et al. Among authors: roggen el. Toxicol Lett. 2022 Mar 1;356:89-99. doi: 10.1016/j.toxlet.2021.12.009. Epub 2021 Dec 15. Toxicol Lett. 2022. PMID: 34921933 Free article.
One science-driven approach for the regulatory implementation of alternative methods: A multi-sector perspective.
Dal Negro G, Eskes C, Belz S, Bertein C, Chlebus M, Corvaro M, Corvi R, Dhalluin S, Halder M, Harvey J, Hermann M, Hoffmann-Dörr S, Kilian K, Lambrigts D, Laroche C, Louhimies S, Mahony C, Manou I, McNamee P, Prieto P, Reid K, Roggen E, Schutte K, Stirling C, Uhlrich S, Weissenhorn R, Whelan M. Dal Negro G, et al. Regul Toxicol Pharmacol. 2018 Nov;99:33-49. doi: 10.1016/j.yrtph.2018.08.002. Epub 2018 Aug 8. Regul Toxicol Pharmacol. 2018. PMID: 30098372 Free article.
Safer chemicals using less animals: kick-off of the European ONTOX project.
Vinken M, Benfenati E, Busquet F, Castell J, Clevert DA, de Kok TM, Dirven H, Fritsche E, Geris L, Gozalbes R, Hartung T, Jennen D, Jover R, Kandarova H, Kramer N, Krul C, Luechtefeld T, Masereeuw R, Roggen E, Schaller S, Vanhaecke T, Yang C, Piersma AH. Vinken M, et al. Toxicology. 2021 Jun 30;458:152846. doi: 10.1016/j.tox.2021.152846. Epub 2021 Jun 30. Toxicology. 2021. PMID: 34216698 Free article. Review.
In vitro RHE skin sensitisation assays: Applicability to challenging substances.
Mehling A, Adriaens E, Casati S, Hubesch B, Irizar A, Klaric M, Letasiova S, Manou I, Müller BP, Roggen E, van Vliet E, Basketter D. Mehling A, et al. Regul Toxicol Pharmacol. 2019 Nov;108:104473. doi: 10.1016/j.yrtph.2019.104473. Epub 2019 Sep 5. Regul Toxicol Pharmacol. 2019. PMID: 31494190 Free article.
Developing a framework for assessing chemical respiratory sensitization: A workshop report.
North CM, Ezendam J, Hotchkiss JA, Maier C, Aoyama K, Enoch S, Goetz A, Graham C, Kimber I, Karjalainen A, Pauluhn J, Roggen EL, Selgrade M, Tarlo SM, Chen CL. North CM, et al. Among authors: roggen el. Regul Toxicol Pharmacol. 2016 Oct;80:295-309. doi: 10.1016/j.yrtph.2016.06.006. Epub 2016 Jul 7. Regul Toxicol Pharmacol. 2016. PMID: 27396307
Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.
Gordon S, Daneshian M, Bouwstra J, Caloni F, Constant S, Davies DE, Dandekar G, Guzman CA, Fabian E, Haltner E, Hartung T, Hasiwa N, Hayden P, Kandarova H, Khare S, Krug HF, Kneuer C, Leist M, Lian G, Marx U, Metzger M, Ott K, Prieto P, Roberts MS, Roggen EL, Tralau T, van den Braak C, Walles H, Lehr CM. Gordon S, et al. Among authors: roggen el. ALTEX. 2015;32(4):327-78. doi: 10.14573/altex.1510051. ALTEX. 2015. PMID: 26536291 Free article.
69 results