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Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition.
Deben C, Boullosa LF, Fortes FR, De La Hoz EC, Le Compte M, Seghers S, Peeters M, Vanlanduit S, Lin A, Dijkstra KK, Van Schil P, Hendriks JMH, Prenen H, Roeyen G, Lardon F, Smits E. Deben C, et al. Among authors: roeyen g. J Exp Clin Cancer Res. 2024 Mar 22;43(1):88. doi: 10.1186/s13046-024-03012-z. J Exp Clin Cancer Res. 2024. PMID: 38515178 Free PMC article.
Targeting hedgehog signaling in pancreatic ductal adenocarcinoma.
Quatannens D, Verhoeven Y, Van Dam P, Lardon F, Prenen H, Roeyen G, Peeters M, Smits ELJ, Van Audenaerde J. Quatannens D, et al. Among authors: roeyen g. Pharmacol Ther. 2022 Aug;236:108107. doi: 10.1016/j.pharmthera.2022.108107. Epub 2022 Jan 7. Pharmacol Ther. 2022. PMID: 34999181 Review.
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer.
Le Compte M, De La Hoz EC, Peeters S, Fortes FR, Hermans C, Domen A, Smits E, Lardon F, Vandamme T, Lin A, Vanlanduit S, Roeyen G, Van Laere S, Prenen H, Peeters M, Deben C. Le Compte M, et al. Among authors: roeyen g. NPJ Precis Oncol. 2023 Dec 8;7(1):128. doi: 10.1038/s41698-023-00480-y. NPJ Precis Oncol. 2023. PMID: 38066116 Free PMC article.
Novel combination immunotherapy for pancreatic cancer: potent anti-tumor effects with CD40 agonist and interleukin-15 treatment.
Van Audenaerde JR, Marcq E, von Scheidt B, Davey AS, Oliver AJ, De Waele J, Quatannens D, Van Loenhout J, Pauwels P, Roeyen G, Lardon F, Slaney CY, Peeters M, Kershaw MH, Darcy PK, Smits EL. Van Audenaerde JR, et al. Among authors: roeyen g. Clin Transl Immunology. 2020 Aug 15;9(8):e1165. doi: 10.1002/cti2.1165. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32821382 Free PMC article.
Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells.
Van Audenaerde JRM, De Waele J, Marcq E, Van Loenhout J, Lion E, Van den Bergh JMJ, Jesenofsky R, Masamune A, Roeyen G, Pauwels P, Lardon F, Peeters M, Smits ELJ. Van Audenaerde JRM, et al. Among authors: roeyen g. Oncotarget. 2017 May 25;8(34):56968-56979. doi: 10.18632/oncotarget.18185. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915646 Free PMC article.
72 results