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Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle PA, Abdullah Z. Hackstein CP, et al. Among authors: roers a. J Hepatol. 2023 Jul;79(1):150-166. doi: 10.1016/j.jhep.2023.02.026. Epub 2023 Mar 2. J Hepatol. 2023. PMID: 36870611 Free article.
Integrin β1-mediated mast cell immune-surveillance of blood vessel content.
Link K, Muhandes L, Polikarpova A, Lämmermann T, Sixt M, Fässler R, Roers A. Link K, et al. Among authors: roers a. J Allergy Clin Immunol. 2024 Apr 16:S0091-6749(24)00362-2. doi: 10.1016/j.jaci.2024.03.022. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 38636606 Free article.
Individualised immunosuppression with intravenously administered donor-derived modified immune cells compared with standard of care in living donor kidney transplantation (TOL-2 Study): protocol for a multicentre, open-label, phase II, randomised controlled trial.
Morath C, Schmitt A, Schmitt M, Wang L, Kleist C, Opelz G, Süsal C, Tran TH, Scherer S, Schwenger V, Kemmner S, Fischereder M, Stangl M, Hauser IA, Sommerer C, Nusshag C, Kälble F, Speer C, Benning L, Bischofs C, Sauer S, Schubert ML, Kunz A, Hückelhoven-Krauss A, Neuber B, Mehrabi A, Schwab C, Waldherr R, Sander A, Büsch C, Czock D, Böhmig GA, Reiser J, Roers A, Müller-Tidow C, Terness P, Zeier M, Daniel V, Schaier M. Morath C, et al. Among authors: roers a. BMJ Open. 2022 Nov 11;12(11):e066128. doi: 10.1136/bmjopen-2022-066128. BMJ Open. 2022. PMID: 36368749 Free PMC article.
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity.
Luca D, Lee S, Hirota K, Okabe Y, Uehori J, Izawa K, Lanz AL, Schütte V, Sivri B, Tsukamoto Y, Hauck F, Behrendt R, Roers A, Fujita T, Nishikomori R, Lee-Kirsch MA, Kato H. Luca D, et al. Among authors: roers a. Sci Adv. 2024 Mar;10(9):eadk0820. doi: 10.1126/sciadv.adk0820. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427731 Free PMC article.
A call to adapt the regulation of HLA testing for T cell receptor-based therapeutics.
Meyer M, Mahr A, Brewer J, Daniel V, Dell'Aringa J, Goldstone T, Hersey S, Johnston I, Larson P, Loveridge M, MacBeath G, Moyer M, Nagorsen D, Papa S, Peiser L, Ranade K, Rizzi R, Roers A, Schendel D, Sivakumar P, Tran E, Türeci Ö, Weigand L, Wennborg A, Williams D, Yee C, Britten CM. Meyer M, et al. Among authors: roers a. Nat Rev Drug Discov. 2024 Jan;23(1):1-2. doi: 10.1038/d41573-023-00189-4. Nat Rev Drug Discov. 2024. PMID: 38030734 No abstract available.
Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis.
Dressel N, Natusch L, Munz CM, Costas Ramon S, Morcos MNF, Loff A, Hiller B, Haase C, Schulze L, Müller P, Lesche M, Dahl A, Luksch H, Rösen-Wolff A, Roers A, Behrendt R, Gerbaulet A. Dressel N, et al. Among authors: roers a. Cancer Res. 2023 Sep 1;83(17):2858-2872. doi: 10.1158/0008-5472.CAN-22-3860. Cancer Res. 2023. PMID: 37335136
142 results