Roerink SF - Search Results

1

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

Roerink SF, van Schendel R, Tijsterman M. Roerink SF, et al. Genome Res. 2014 Jun;24(6):954-62. doi: 10.1101/gr.170431.113. Epub 2014 Mar 10. Genome Res. 2014. PMID: 24614976 Free PMC article.

2

A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis.

Roerink SF, Koole W, Stapel LC, Romeijn RJ, Tijsterman M. Roerink SF, et al. PLoS Genet. 2012 Jun;8(6):e1002800. doi: 10.1371/journal.pgen.1002800. Epub 2012 Jun 28. PLoS Genet. 2012. PMID: 22761594 Free PMC article.

3

Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.

van Schendel R, Roerink SF, Portegijs V, van den Heuvel S, Tijsterman M. van Schendel R, et al. Among authors: roerink sf. Nat Commun. 2015 Jun 16;6:7394. doi: 10.1038/ncomms8394. Nat Commun. 2015. PMID: 26077599 Free PMC article.

4

Genome sequencing of normal cells reveals developmental lineages and mutational processes.

Behjati S, Huch M, van Boxtel R, Karthaus W, Wedge DC, Tamuri AU, Martincorena I, Petljak M, Alexandrov LB, Gundem G, Tarpey PS, Roerink S, Blokker J, Maddison M, Mudie L, Robinson B, Nik-Zainal S, Campbell P, Goldman N, van de Wetering M, Cuppen E, Clevers H, Stratton MR. Behjati S, et al. Nature. 2014 Sep 18;513(7518):422-425. doi: 10.1038/nature13448. Epub 2014 Jun 29. Nature. 2014. PMID: 25043003 Free PMC article.

5

Tissue-specific mutation accumulation in human adult stem cells during life.

Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R. Blokzijl F, et al. Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3. Nature. 2016. PMID: 27698416 Free PMC article.

6

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.

Garaycoechea JI, Crossan GP, Langevin F, Mulderrig L, Louzada S, Yang F, Guilbaud G, Park N, Roerink S, Nik-Zainal S, Stratton MR, Patel KJ. Garaycoechea JI, et al. Nature. 2018 Jan 11;553(7687):171-177. doi: 10.1038/nature25154. Epub 2018 Jan 3. Nature. 2018. PMID: 29323295 Free PMC article.

7

Intra-tumour diversification in colorectal cancer at the single-cell level.

Roerink SF, Sasaki N, Lee-Six H, Young MD, Alexandrov LB, Behjati S, Mitchell TJ, Grossmann S, Lightfoot H, Egan DA, Pronk A, Smakman N, van Gorp J, Anderson E, Gamble SJ, Alder C, van de Wetering M, Campbell PJ, Stratton MR, Clevers H. Roerink SF, et al. Nature. 2018 Apr;556(7702):457-462. doi: 10.1038/s41586-018-0024-3. Epub 2018 Apr 11. Nature. 2018. PMID: 29643510

8

Allosteric modulators affect the internalization of human adenosine A1 receptors.

Klaasse EC, van den Hout G, Roerink SF, de Grip WJ, Ijzerman AP, Beukers MW. Klaasse EC, et al. Among authors: roerink sf. Eur J Pharmacol. 2005 Oct 17;522(1-3):1-8. doi: 10.1016/j.ejphar.2005.08.052. Epub 2005 Oct 7. Eur J Pharmacol. 2005. PMID: 16214128

9

Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Klaasse E, de Ligt RA, Roerink SF, Lorenzen A, Milligan G, Leurs R, IJzerman AP. Klaasse E, et al. Among authors: roerink sf. Eur J Pharmacol. 2004 Sep 19;499(1-2):91-8. doi: 10.1016/j.ejphar.2004.07.108. Eur J Pharmacol. 2004. PMID: 15363955

10

A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptor.

Chang LC, von Frijtag Drabbe Künzel JK, Mulder-Krieger T, Spanjersberg RF, Roerink SF, van den Hout G, Beukers MW, Brussee J, Ijzerman AP. Chang LC, et al. Among authors: roerink sf. J Med Chem. 2005 Mar 24;48(6):2045-53. doi: 10.1021/jm049597+. J Med Chem. 2005. PMID: 15771447

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