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(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
Dzien P, Tee SS, Kettunen MI, Lyons SK, Larkin TJ, Timm KN, Hu DE, Wright A, Rodrigues TB, Serrao EM, Marco-Rius I, Mannion E, D'Santos P, Kennedy BW, Brindle KM. Dzien P, et al. Among authors: rodrigues tb. Magn Reson Med. 2016 Aug;76(2):391-401. doi: 10.1002/mrm.25879. Epub 2015 Sep 21. Magn Reson Med. 2016. PMID: 26388418 Free PMC article.
Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.
Marco-Rius I, Tayler MC, Kettunen MI, Larkin TJ, Timm KN, Serrao EM, Rodrigues TB, Pileio G, Ardenkjaer-Larsen JH, Levitt MH, Brindle KM. Marco-Rius I, et al. Among authors: rodrigues tb. NMR Biomed. 2013 Dec;26(12):1696-704. doi: 10.1002/nbm.3005. Epub 2013 Aug 15. NMR Biomed. 2013. PMID: 23946252 Free PMC article.
Development of Timd2 as a reporter gene for MRI.
Patrick PS, Rodrigues TB, Kettunen MI, Lyons SK, Neves AA, Brindle KM. Patrick PS, et al. Among authors: rodrigues tb. Magn Reson Med. 2016 Apr;75(4):1697-707. doi: 10.1002/mrm.25750. Epub 2015 May 15. Magn Reson Med. 2016. PMID: 25981669 Free PMC article.
Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors.
Gallagher FA, Sladen H, Kettunen MI, Serrao EM, Rodrigues TB, Wright A, Gill AB, McGuire S, Booth TC, Boren J, McIntyre A, Miller JL, Lee SH, Honess D, Day SE, Hu DE, Howat WJ, Harris AL, Brindle KM. Gallagher FA, et al. Among authors: rodrigues tb. Cancer Res. 2015 Oct 1;75(19):4109-18. doi: 10.1158/0008-5472.CAN-15-0857. Epub 2015 Aug 6. Cancer Res. 2015. PMID: 26249175 Free PMC article.
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging.
Neves AA, Wainman YA, Wright A, Kettunen MI, Rodrigues TB, McGuire S, Hu DE, Bulat F, Geninatti Crich S, Stöckmann H, Leeper FJ, Brindle KM. Neves AA, et al. Among authors: rodrigues tb. Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1286-90. doi: 10.1002/anie.201509858. Epub 2015 Dec 3. Angew Chem Int Ed Engl. 2016. PMID: 26633082 Free PMC article.
76 results