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HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease.
Zhang J, Qin Y, Martinez M, Flores-Bellver M, Rodrigues M, Dinabandhu A, Cao X, Deshpande M, Qin Y, Aparicio-Domingo S, Rui Y, Tzeng SY, Salman S, Yuan J, Scott AW, Green JJ, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: rodrigues m. J Clin Invest. 2021 Jun 15;131(12):e139202. doi: 10.1172/JCI139202. J Clin Invest. 2021. PMID: 34128478 Free PMC article.
VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy.
Rodrigues M, Xin X, Jee K, Babapoor-Farrokhran S, Kashiwabuchi F, Ma T, Bhutto I, Hassan SJ, Daoud Y, Baranano D, Solomon S, Lutty G, Semenza GL, Montaner S, Sodhi A. Rodrigues M, et al. Diabetes. 2013 Nov;62(11):3863-73. doi: 10.2337/db13-0014. Epub 2013 Jul 24. Diabetes. 2013. PMID: 23884892 Free PMC article.
Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.
Xin X, Rodrigues M, Umapathi M, Kashiwabuchi F, Ma T, Babapoor-Farrokhran S, Wang S, Hu J, Bhutto I, Welsbie DS, Duh EJ, Handa JT, Eberhart CG, Lutty G, Semenza GL, Montaner S, Sodhi A. Xin X, et al. Among authors: rodrigues m. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3425-34. doi: 10.1073/pnas.1217091110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959876 Free PMC article.
Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.
Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hu K, et al. Among authors: rodrigues m. Oncotarget. 2016 Feb 16;7(7):7816-28. doi: 10.18632/oncotarget.6868. Oncotarget. 2016. PMID: 26761211 Free PMC article.
Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia.
Meng Q, Qin Y, Deshpande M, Kashiwabuchi F, Rodrigues M, Lu Q, Ren H, Elisseeff JH, Semenza GL, Montaner SV, Sodhi A. Meng Q, et al. Among authors: rodrigues m. Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4514-4523. doi: 10.1167/iovs.17-21974. Invest Ophthalmol Vis Sci. 2017. PMID: 28873177 Free PMC article.
ANGPTL4 influences the therapeutic response of patients with neovascular age-related macular degeneration by promoting choroidal neovascularization.
Qin Y, Dinabandhu A, Cao X, Sanchez JC, Jee K, Rodrigues M, Guo C, Zhang J, Vancel J, Menon D, Khan NS, Ma T, Tzeng SY, Daoud Y, Green JJ, Semenza GL, Montaner S, Sodhi A. Qin Y, et al. Among authors: rodrigues m. JCI Insight. 2022 Jul 8;7(13):e157896. doi: 10.1172/jci.insight.157896. JCI Insight. 2022. PMID: 35653189 Free PMC article.
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy.
Babapoor-Farrokhran S, Jee K, Puchner B, Hassan SJ, Xin X, Rodrigues M, Kashiwabuchi F, Ma T, Hu K, Deshpande M, Daoud Y, Solomon S, Wenick A, Lutty GA, Semenza GL, Montaner S, Sodhi A. Babapoor-Farrokhran S, et al. Among authors: rodrigues m. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3030-9. doi: 10.1073/pnas.1423765112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26039997 Free PMC article.
Correction: Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.
Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A. Hu K, et al. Among authors: rodrigues m. Oncotarget. 2021 Mar 2;12(5):519-520. doi: 10.18632/oncotarget.27780. eCollection 2021 Mar 2. Oncotarget. 2021. PMID: 33747364 Free PMC article.
4,432 results