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The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: rodrigues fp. Mitochondrion. 2011 Mar;11(2):255-63. doi: 10.1016/j.mito.2010.10.008. Epub 2010 Oct 31. Mitochondrion. 2011. PMID: 21044702
The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: rodrigues fp. Toxicol Appl Pharmacol. 2011 Jun 15;253(3):282-9. doi: 10.1016/j.taap.2011.04.011. Epub 2011 Apr 27. Toxicol Appl Pharmacol. 2011. PMID: 21549140 Free article.
C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
Marín-Prida J, Pentón-Rol G, Rodrigues FP, Alberici LC, Stringhetta K, Leopoldino AM, Naal Z, Polizello AC, Llópiz-Arzuaga A, Rosa MN, Liberato JL, Santos WF, Uyemura SA, Pentón-Arias E, Curti C, Pardo-Andreu GL. Marín-Prida J, et al. Among authors: rodrigues fp. Brain Res Bull. 2012 Dec 1;89(5-6):159-67. doi: 10.1016/j.brainresbull.2012.08.011. Epub 2012 Sep 7. Brain Res Bull. 2012. PMID: 22982368 Free article.
Ca(2+) binding to c-state of adenine nucleotide translocase (ANT)-surrounding cardiolipins enhances (ANT)-Cys(56) relative mobility: a computational-based mitochondrial permeability transition study.
Pestana CR, Silva CH, Pardo-Andreu GL, Rodrigues FP, Santos AC, Uyemura SA, Curti C. Pestana CR, et al. Among authors: rodrigues fp. Biochim Biophys Acta. 2009 Mar;1787(3):176-82. doi: 10.1016/j.bbabio.2008.12.013. Epub 2009 Jan 7. Biochim Biophys Acta. 2009. PMID: 19161974 Free article.
JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro.
Nuñez-Figueredo Y, Ramírez-Sánchez J, Delgado-Hernández R, Porto-Verdecia M, Ochoa-Rodríguez E, Verdecia-Reyes Y, Marin-Prida J, González-Durruthy M, Uyemura SA, Rodrigues FP, Curti C, Souza DO, Pardo-Andreu GL. Nuñez-Figueredo Y, et al. Among authors: rodrigues fp. Eur J Pharmacol. 2014 Mar 5;726:57-65. doi: 10.1016/j.ejphar.2014.01.021. Eur J Pharmacol. 2014. PMID: 24462350 Free article.
(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM. dos Santos GA, et al. Among authors: rodrigues fp. Leukemia. 2012 Mar;26(3):451-60. doi: 10.1038/leu.2011.216. Epub 2011 Aug 26. Leukemia. 2012. PMID: 21869839
66 results